Craniopharyngioma medical therapy: Difference between revisions

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#Potential short-term and long-term toxicity.
#Potential short-term and long-term toxicity.


Treatment options for newly diagnosed childhood craniopharyngioma include the following:
Treatment options for newly diagnosed craniopharyngioma include the following:
 
*Radical surgery with or without radiation therapy.
Radical surgery with or without radiation therapy.
*Subtotal resection with radiation therapy.
Subtotal resection with radiation therapy.
*Primary cyst drainage with or without radiation therapy.
Primary cyst drainage with or without radiation therapy.


====Recurrent craniopharyngioma====
====Recurrent craniopharyngioma====

Revision as of 16:35, 23 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Patients with craniopharyngioma have many treatment options. The selection depends on the size, location of the tumor. The options are surgery, radiation therapy, chemotherapy, or a combination of these methods.

Medical Therapy

For treatment purposes, patients are grouped as having newly diagnosed or recurrent disease.[1]

Newly diagnosed craniopharyngioma

There is no consensus on the optimal treatment for newly diagnosed craniopharyngioma, in part because of the lack of prospective randomized trials that compare the different treatment options. Treatment is individualized on the basis of factors that include the following:

  1. Tumor size
  2. Tumor location
  3. Extension of the tumor.
  4. Potential short-term and long-term toxicity.

Treatment options for newly diagnosed craniopharyngioma include the following:

  • Radical surgery with or without radiation therapy.
  • Subtotal resection with radiation therapy.
  • Primary cyst drainage with or without radiation therapy.

Recurrent craniopharyngioma

  • Surgery
  • Radiation therapy, including radiosurgery
  • Intracavitary instillation of radioactive P-32, bleomycin, or interferon-alpha, for those with cystic recurrences
  • Systemic interferon

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