Sandbox mona: Difference between revisions
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:::*Regimens :Cryotherapy with liquid nitrogen {{or}} Surgical removal{{or}} TCA or BCA 80%–90% solution | :::*Regimens :Cryotherapy with liquid nitrogen {{or}} Surgical removal{{or}} TCA or BCA 80%–90% solution | ||
:::*Note:Management of intra-anal warts should include consultation with a specialist. | :::*Note:Management of intra-anal warts should include consultation with a specialist. | ||
Granuloma Inguinale (Donovanosis) | Granuloma Inguinale (Donovanosis) | ||
Preferred regimen:[[Azithromycin]] 1 g PO once per week {{or}} 500 mg PO qd for 3 weeks and until all lesions have completely healed | :::*Preferred regimen:[[Azithromycin]] 1 g PO once per week {{or}} 500 mg PO qd for 3 weeks and until all lesions have completely healed | ||
Alternative Regimen:[[Doxycycline]] 100 mg PO bid for 3 weeks {{or}}[[Ciprofloxacin]] 750 mg PO bid for 3 weeks {{or}} | :::*Alternative Regimen:[[Doxycycline]] 100 mg PO bid for 3 weeks {{or}}[[Ciprofloxacin]] 750 mg PO bid for 3 weeks {{or}} | ||
[[Erythromycin]] base 500 mg PO qid for 3 weeks {{or}} [[Trimethoprim-sulfamethoxazole]] one double-strength (160 mg/800 mg) PO bid for 3 weeks | [[Erythromycin]] base 500 mg PO qid for 3 weeks {{or}} [[Trimethoprim-sulfamethoxazole]] one double-strength (160 mg/800 mg) PO bid for 3 weeks | ||
Pregnant and lactating women | |||
treated with a macrolide regimen (erythromycin or azithromycin). The addition of an aminoglycoside (gentamicin 1 mg/kg IV every 8 hours) can be considered if improvement is not evident within the first few days of therapy. | :::*Preferred regimen:treated with a macrolide regimen (erythromycin or azithromycin). The addition of an aminoglycoside (gentamicin 1 mg/kg IV every 8 hours) can be considered if improvement is not evident within the first few days of therapy. | ||
HIV Infection | HIV Infection | ||
:::*Preferred regimen:[[Azithromycin]] 1 g PO once per week {{or}} 500 mg PO qd for 3 weeks and until all lesions have completely healed | |||
Preferred regimen:[[Azithromycin]] 1 g PO once per week {{or}} 500 mg PO qd for 3 weeks and until all lesions have completely healed | :::*Alternative Regimen:[[Doxycycline]] 100 mg PO bid for 3 weeks {{or}}[[Ciprofloxacin]] 750 mg PO bid for 3 weeks {{or}} | ||
Alternative Regimen:[[Doxycycline]] 100 mg PO bid for 3 weeks {{or}}[[Ciprofloxacin]] 750 mg PO bid for 3 weeks {{or}} | |||
[[Erythromycin]] base 500 mg PO qid for 3 weeks {{or}} [[Trimethoprim-sulfamethoxazole]] one double-strength (160 mg/800 mg) PO bid for 3 weeks | [[Erythromycin]] base 500 mg PO qid for 3 weeks {{or}} [[Trimethoprim-sulfamethoxazole]] one double-strength (160 mg/800 mg) PO bid for 3 weeks | ||
The addition of an aminoglycoside (gentamicin 1 mg/kg IV every 8 hours) can be considered if improvement is not evident within the first few days of therapy. | :::*Note:The addition of an aminoglycoside (gentamicin 1 mg/kg IV every 8 hours) can be considered if improvement is not evident within the first few days of therapy. | ||
Revision as of 16:51, 2 July 2015
- 1.Preferred regimen for External Anogenital Warts (i.e., penis, groin, scrotum, vulva, perineum, external anus, and perianus)
- 1.1 Patient-Applied::Imiquimod 3.75% or 5% cream ORPodofilox 0.5% solution or gel OR Sinecatechins 15% ointment
- 1.2 Provider-Administered:Cryotherapy with liquid nitrogen or cryoprobe OR Surgical removal either by tangential scissor excision, tangential shave excision, curettage, laser,or electrosurgery OR Trichloroacetic acid (TCA) or Bichloroacetic acid (BCA) 80%-90% solution
- Note(1):Many persons with external anal warts also have intra-anal warts. Thus, persons with external anal warts might benefit from an inspection of the anal canal by digital examination, standard anoscopy, or high-resolution anoscopy.
- Note(2):Might weaken condoms and vaginal diaphragms.
- 2.Alternative Regimens for External Genital Warts
- 2.1 Urethral Meatus Warts
- Regimens :Cryotherapy with liquid nitrogen OR Surgical removal
- 2.2 Vaginal Warts
- Regimens:Cryotherapy with liquid nitrogen. OR Surgical removal OR TCA or BCA 80%–90% solution
- Note: The use of a cryoprobe in the vagina is not recommended because of the risk for vaginal perforation and fistula formation
- 2.3 Cervical Warts
- Regimen: Cryotherapy with liquid nitrogen OR Surgical removal OR TCA or BCA 80%–90% solution
- Note: Management of cervical warts should include consultation with a specialist.For women who have exophytic cervical warts, a biopsy evaluation to exclude high-grade SIL must be performed before treatment is initiated.
- 2.4 Intra-anal Warts
- Regimens :Cryotherapy with liquid nitrogen OR Surgical removalOR TCA or BCA 80%–90% solution
- Note:Management of intra-anal warts should include consultation with a specialist.
Granuloma Inguinale (Donovanosis)
- Preferred regimen:Azithromycin 1 g PO once per week OR 500 mg PO qd for 3 weeks and until all lesions have completely healed
- Alternative Regimen:Doxycycline 100 mg PO bid for 3 weeks ORCiprofloxacin 750 mg PO bid for 3 weeks OR
Erythromycin base 500 mg PO qid for 3 weeks OR Trimethoprim-sulfamethoxazole one double-strength (160 mg/800 mg) PO bid for 3 weeks
Pregnant and lactating women
:::*Preferred regimen:treated with a macrolide regimen (erythromycin or azithromycin). The addition of an aminoglycoside (gentamicin 1 mg/kg IV every 8 hours) can be considered if improvement is not evident within the first few days of therapy.
HIV Infection
- Preferred regimen:Azithromycin 1 g PO once per week OR 500 mg PO qd for 3 weeks and until all lesions have completely healed
- Alternative Regimen:Doxycycline 100 mg PO bid for 3 weeks ORCiprofloxacin 750 mg PO bid for 3 weeks OR
Erythromycin base 500 mg PO qid for 3 weeks OR Trimethoprim-sulfamethoxazole one double-strength (160 mg/800 mg) PO bid for 3 weeks
- Note:The addition of an aminoglycoside (gentamicin 1 mg/kg IV every 8 hours) can be considered if improvement is not evident within the first few days of therapy.