Fever of unknown origin other diagnostic studies: Difference between revisions
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Hepatobiliary pathology may be detected by abdominal ultrasonography. An abdominal [[CT scan]] may show [[infection]] or malignancy of the visceral organs. | Hepatobiliary pathology may be detected by abdominal ultrasonography. An abdominal [[CT scan]] may show [[infection]] or malignancy of the visceral organs. | ||
[[ | [[Positron emission tomography]] using radioactively labelled [[fluorodeoxyglucose]] (FDG) has been reported to have a [[Sensitivity (tests)|sensitivity]] of 84% and a [[Specificity (tests)| specificity]] of 86% for localizing the nidus of fever of unknown origin.<ref>{{cite journal | author = Meller J, Altenvoerde G, Munzel U, Jauho A, Behe M, Gratz S, Luig H, Becker W | title = Fever of unknown origin: prospective comparison of [18F]FDG imaging with a double-head coincidence camera and gallium-67 citrate SPET. | journal = Eur J Nucl Med. | volume = 27| issue = 11 | pages = 1617-25 | year = 2000 | id = PMID 11105817}}</ref> | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
Revision as of 21:43, 23 March 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; fever/pyrexia of obscured/undetermined/uncertain/unidentifiable/unknown focus/origin/source; fever/pyrexia without a focus/origin/source; FUO; PUO
Imaging Studies
Echocardiography should be performed when suspecting endocarditis.
Hepatobiliary pathology may be detected by abdominal ultrasonography. An abdominal CT scan may show infection or malignancy of the visceral organs.
Positron emission tomography using radioactively labelled fluorodeoxyglucose (FDG) has been reported to have a sensitivity of 84% and a specificity of 86% for localizing the nidus of fever of unknown origin.[1]
Other Diagnostic Studies
Invasive techniques (biopsy and laparotomy for pathological and bacteriological examination) may be required to obtain a definitive diagnosis.[2][3][4]
Defervescence within 72 hours of discontinuing medication indicates drug fever.
An infectious etiology is likely if abatement of fever occurs after the administration of antibiotics. Therapeutic trials of antimicrobial agents may be considered if other techniques fail to disclose the cause of FUO.[2]
References
- ↑ Meller J, Altenvoerde G, Munzel U, Jauho A, Behe M, Gratz S, Luig H, Becker W (2000). "Fever of unknown origin: prospective comparison of [18F]FDG imaging with a double-head coincidence camera and gallium-67 citrate SPET". Eur J Nucl Med. 27 (11): 1617–25. PMID 11105817.
- ↑ 2.0 2.1 Mandell's Principles and Practices of Infection Diseases 6th Edition (2004) by Gerald L. Mandell MD, MACP, John E. Bennett MD, Raphael Dolin MD, ISBN 0-443-06643-4 · Hardback · 4016 Pages Churchill Livingstone
- ↑ Harrison's Principles of Internal Medicine 16th Edition, The McGraw-Hill Companies, ISBN 0-07-140235-7
- ↑ The Oxford Textbook of Medicine Edited by David A. Warrell, Timothy M. Cox and John D. Firth with Edward J. Benz, Fourth Edition (2003), Oxford University Press, ISBN 0-19-262922-0