Seronegative spondyloarthritis: Difference between revisions
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===ASAS classification criteria for peripheral spondyloarthritis=== | ===ASAS classification criteria for peripheral spondyloarthritis=== | ||
*The Assessment of SpondyloArthritis international Society classification criteria for peripheral spondyloarthritis (peripheral SpA) include:<ref name="pmid21163805">{{cite journal| author=Zeidler H, Amor B| title=The Assessment in Spondyloarthritis International Society (ASAS) classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general: the spondyloarthritis concept in progress. | journal=Ann Rheum Dis | year= 2011 | volume= 70 | issue= 1 | pages= 1-3 | pmid=21163805 | doi=10.1136/ard.2010.135889 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21163805 }} </ref> | |||
:'''Arthritis or Enthesitis or Dactylitis''' | |||
: '''PLUS ≥ 1 of:''' | |||
:*Psoriasis | |||
:*Inflammatory bowel disease | |||
:*Preceding infection | |||
:*HLA-B27 | |||
:*Uveitis | |||
:*Sacroiliitis on imaging (radiograph or MRI) | |||
: '''PLUS ≥ 2 of:''' | |||
:*Arthritis | |||
:*Entheistis | |||
:*Dactylitis | |||
:*Inflammatory back pain in the past | |||
:*Positive family history of SpA | |||
==Differential== | ==Differential== | ||
Revision as of 17:35, 9 April 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
"Seronegative" refers to the fact that these diseases are negative for Rheumatoid factor and CCP in the serum.
Classsiication
Algorithm showing classification of seronegative spondyloarthritis[1]
| Seronegative Spondyloarthritis (SpA) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Axial SpA including Ankylosing spondylitis | Peripheral SpA | Psoriatic arthritis | Reactive arthritis | Inflammatory bowel disease related arthritis | Juvenile spondyloarthritis | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Classification Criteria
ASAS classification criteria for axial spondyloarthritis (axial SpA)
The Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (axial SpA) include:[2]
- Patient with back pain ≥ 3 months and age of onset <45 years should fulfill either of the two criteria:
- Sacroiliitis on imaging* plus ≥ 1 feature of SpA**
- HLA-B27 plus ≥ 2 feature of SpA**
- *Sacroiliitis on imaging:
- Active (acute) inflammation on MRI highly suggestive of sacroiliitis associated with SpA
- OR
- Definite radiographic sacroillitis accorging to modified New York criteria
- **SpA features:
- Inflammatroy back pain
- Arthritis
- Enthesotos (heel)
- Uveitis
- Dactylitis
- Psoriasis
- Crohn's disease or ulcerative colitis
- Good response to NSAIDs
- Family history for SpA
- HLA-B27
- Elevated CRP
- *Sacroiliitis on imaging:
ASAS classification criteria for peripheral spondyloarthritis
- The Assessment of SpondyloArthritis international Society classification criteria for peripheral spondyloarthritis (peripheral SpA) include:[3]
- Arthritis or Enthesitis or Dactylitis
- PLUS ≥ 1 of:
- Psoriasis
- Inflammatory bowel disease
- Preceding infection
- HLA-B27
- Uveitis
- Sacroiliitis on imaging (radiograph or MRI)
- PLUS ≥ 2 of:
- Arthritis
- Entheistis
- Dactylitis
- Inflammatory back pain in the past
- Positive family history of SpA
Differential
Diagnosis
These diseases has following conditions in common:
- They are in relation to HLA-B27
- sacroiliitis and spondylitis are present in them.
- familial aggregation occurs
- Overlap is likely in them
- rheumatoid factor is not present
References
- ↑ Dougados M, Baeten D (2011). "Spondyloarthritis". Lancet. 377 (9783): 2127–37. doi:10.1016/S0140-6736(11)60071-8. PMID 21684383.
- ↑ Rudwaleit M, van der Heijde D, Landewé R, Listing J, Akkoc N, Brandt J; et al. (2009). "The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection". Ann Rheum Dis. 68 (6): 777–83. doi:10.1136/ard.2009.108233. PMID 19297344.
- ↑ Zeidler H, Amor B (2011). "The Assessment in Spondyloarthritis International Society (ASAS) classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general: the spondyloarthritis concept in progress". Ann Rheum Dis. 70 (1): 1–3. doi:10.1136/ard.2010.135889. PMID 21163805.