Noncompaction cardiomyopathy biopsy: Difference between revisions

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==Cardiac Biopsy==
==Cardiac Biopsy==
*Interstitial [[fibrosis]] was observed in 5/5 patients with isolated noncompaction cardiomyopathy who underwent [[right ventricular biopsy]]<ref>
*Interstitial [[fibrosis]] was observed in 5/5 patients with isolated noncompaction cardiomyopathy who underwent [[right ventricular biopsy]]<ref>
Hamamichi  Y,  Ichida  F,  Hashimoto  I, et al.  Isolated noncompaction of the ventricular myocardium:  ultrafast computer tomography and magnetic resonance imaging. Int J Cardiovasc Imaging.  2001;  17:  305–314.
Hamamichi  Y,  Ichida  F,  Hashimoto  I, et al.  Isolated noncompaction of the ventricular myocardium:  ultrafast computer tomography and magnetic resonance imaging. Int J Cardiovasc Imaging.  2001;  17:  305–314.</ref>
 
*Endomyocardial thickening and subendocardial [[fibroelastosis]] was observed in 3/5 patients who underwent [[right ventricular biopsy]].
</ref>
*Myocyte [[necrosis]] has been observed in areas of trabeculation <ref>Oechslin  EN,  Attenhofer Jost  CH,  Rojas  JR, et al.  Long-term follow-up of 34 adults with isolated left ventricular noncompaction:          a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol.  2000;  36:  493–500.</ref><ref>Finsterer  J,  Stollberger  C,  Feichtinger  H.  Histological appearance of left ventricular hypertrabeculation/noncompaction. Cardiology.  2002;  98:  162–164.</ref>.
*Endomyocardial thickening and subendocardial [[fibroelastosis]] was observed in 3/5 patients who underwent [[right ventricular biopsy]]


==References==
==References==

Latest revision as of 13:45, 6 August 2011

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Both skeletal and cardiac biopsies may reveal abnormal histologic findings.

Skeletal Biopsy

A skeletal biopsy can be performed which may demonstrate inclusion bodies or myopathic changes [1].

Cardiac Biopsy

References

  1. Botto, LD. Left ventricular noncompaction. Orphanet encyclopedia. http://www.orpha.net/data/patho/GB/uk-LVNC.pdf
  2. Hamamichi Y, Ichida F, Hashimoto I, et al. Isolated noncompaction of the ventricular myocardium: ultrafast computer tomography and magnetic resonance imaging. Int J Cardiovasc Imaging. 2001; 17: 305–314.
  3. Oechslin EN, Attenhofer Jost CH, Rojas JR, et al. Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol. 2000; 36: 493–500.
  4. Finsterer J, Stollberger C, Feichtinger H. Histological appearance of left ventricular hypertrabeculation/noncompaction. Cardiology. 2002; 98: 162–164.

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