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| {{familytree/start |summary= Algorithm for diagnosis of CUP}}
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| {{familytree | | | | | | | | | | | A01 | | | | | | | | |A01=Tumor of unknown primary origin}}
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| {{familytree | | | | | | | | | | | |!| | | | | | | | | |}}
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| {{familytree | | | | | | | | | | |boxstyle=text-align: left; | B01 | | | | | | |B01= • Full medical history and physical exam<br> • Basic blood and bichemical analysis<br> • CT scan of chest, abdomen, and pelvis}} | | Cardiac surgery<ref name="pmid23447502">{{cite journal| author=Aya HD, Cecconi M, Hamilton M, Rhodes A| title=Goal-directed therapy in cardiac surgery: a systematic review and meta-analysis. | journal=Br J Anaesth | year= 2013 | volume= 110 | issue= 4 | pages= 510-7 | pmid=23447502 | doi=10.1093/bja/aet020 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23447502 }} </ref> |
| {{familytree | | | | | | | | | | | |!| | | | | | | | | }}
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| {{familytree | | | | | | | | | | | C01 | | | | | | |C01=Histopathologic examination}}
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| {{familytree | | | | |D01| | | | D02| | | | D03 |D01='''Squamous cell carcinoma'''|D02='''Neuroendocrine carcinoma'''|D03='''Adenocarcinoma and poorly differntiated carcinoma'''}}
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| {{familytree | | | | | |!| | | | |boxstyle=text-align: left;|E01| | | | |!| |E01=• Octreoscan<br> • Plasma chromogranin A}}
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| {{familytree | | | | |F01| | | | | | | | | | F02 | |F01=Additional tests specific to location of metastasis|F02=Gender specific tests}}
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| {{familytree | | |,|-|-|+|-|-|-|.| | | | | |,|-|^|-|.| | | }}
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| {{familytree | G01 | | G02 | | G03 | | | | G04 | | G05 | | | |G01=Cervical lymphadenopathy|G02=Inguinal lymphadenopathy|G03=Bone metastasis|G04=Male|G05=Female}}
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| {{familytree |boxstyle=text-align: left;| H01 | | H02 | | H03 | | | | H04 | | H05 | | | |H01=• Panendoscopy<br>• CT scan of head and neck<br>• Diagnostic bilateral amygdalectomy|H02=• Complete clinical examination of external genital organs<br>• Pelvic CT scan or ultrasound|H03=• Anoscopy<br>• Colposcopy (if female)<br>• Complete clinical examination of head and neck<br>• Panendoscopy<br>• Bone scintigraphy<br>• Xrays of painful areas|H04=• PSA<br>• aFP<br>• BHCG|H05=• Mammography<br>• Pelvic ultrasound or CT scan}}
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| {{familytree | | | | | | | | | | | | | | | |!| | | |!| | | | |}}
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| {{familytree | | | | | | | | | | | | | | | |`|-|v|-|'| | | | |}}
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| {{familytree | | | | | | | | | | | | | | | | | I01 | | | | | | |I01=Additional tests specific to location of metastasis}}
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| {{familytree | |,|-|-|-|v|-|-|-|v|-|-|-|v|-|-|-|+|-|-|-|v|-|-|-|v|-|-|-|v|-|-|-|.|}}
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| {{familytree | J01 | | J02 | | J03 | | J04 | | J05 | | J06 | | J07 | | J08 | | J09 |J01=Midline and/or mediastinal lymphadenopathy|J02=Cervical and/or supraclavicular lymphadenopathy|J03=Axillary lymphadenopathy|J04=Liver metastasis|J05=Lung metastasis|J06=Bone metastasis|J07=Single metastasis|J08=Pleural effusion|J09=Periotneal effusion}}
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| {{familytree | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| | | |!| |}}
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| {{familytree/end}}
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