Dyspareunia pathophysiology: Difference between revisions

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{{CMG}} {{AE}}
{{CMG}} {{AE}}
==Overview==
==Overview==
[[Dyspareunia]]  is caused by  [[medical causes]], [[psychological]] problems, and [[pathophysiology]] can be considered as multifactorial, [[multisystemic]], or [[complex]]. [[Dyspareunia]] vary based on the underlying causes. For example, [[Estrogen|estrogen deficiency]] causes [[atrophic vaginitis]] or [[Ectopic|ectopic uterine tissues]] in [[endometriosis]] causes [[dyspareunia]].
[[pathophysiology]] of genito-pelvic pain/ penetration disorder(GPPPD) can be considered as multifactorial, [[multisystemic]], or [[complex]].


==Pathophysiology==
==Pathophysiology==
[[Pathophysiology]] of [[sexual pain disorders]] can be considered as:<ref> 10.1007/978-3-319-52539-6_20</ref><ref name="pmid24811097">{{cite journal |vauthors=Graziottin A, Skaper SD, Fusco M |title=Mast cells in chronic inflammation, pelvic pain and depression in women |journal=Gynecol. Endocrinol. |volume=30 |issue=7 |pages=472–7 |date=July 2014 |pmid=24811097 |doi=10.3109/09513590.2014.911280 |url=}}</ref>
[[Pathophysiology]] of [[sexual pain disorders]] in female can be considered as:<ref> 10.1007/978-3-319-52539-6_20</ref><ref name="pmid24811097">{{cite journal |vauthors=Graziottin A, Skaper SD, Fusco M |title=Mast cells in chronic inflammation, pelvic pain and depression in women |journal=Gynecol. Endocrinol. |volume=30 |issue=7 |pages=472–7 |date=July 2014 |pmid=24811097 |doi=10.3109/09513590.2014.911280 |url=}}</ref>
*'''Multifactorial'''
*'''Multifactorial'''
*'''Multisystemic'''
*'''Multisystemic'''
*'''Complex'''
*'''Complex'''
'''Multifactorial''':
'''Multifactorial''':
*[[Biological]], [[psychosexual]], relational factors can coexist in a woman complaining of [[Coitus|coital]] pain. Over time, these different factors may act as predisposing, precipitating, or perpetuating sexual pain disorders.<br>
*[[Biological]], [[psychosexual]], relational factors can coexist and interact to perpetuate and maintain a woman’s pain response in a woman complaining of [[Coitus|coital]] pain. Over time, these different factors may act as predisposing, precipitating, or perpetuating sexual pain disorders.<br>
'''Multisystemic''': sexual function involves:
'''Multisystemic''': sexual function involves:
*[[Nervous system]]
*[[Nervous system]]
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*[[Vascular system]]
*[[Vascular system]]
*[[Immunological system|Immunological systems]]
*[[Immunological system|Immunological systems]]
*[[Vaginal]] ecosystem: Vaginal receptiveness may be further modulated by; psychosexual, [[mental]], [[interpersonal]] factors that may result in poor arousal with [[vaginal dryness]]. Fear of penetration, general [[muscular]] arousal secondary to [[anxiety]], defensive [[contraction]] of the peri-vaginal [[muscles]], leading to lifelong [[vaginismus]].<br>
*[[Vaginal]] ecosystem: Vaginal receptiveness may be further modulated by; psychosexual, [[mental]], [[interpersonal]] factors that may result in poor [[arousal]] with [[vaginal dryness]]. Fear of penetration, general [[muscular]] arousal secondary to [[anxiety]], defensive [[contraction]] of the peri-vaginal [[muscles]], leading to lifelong [[vaginismus]].<br>




'''Complex:'''Coital pain is greater than the simple peripheral [[tissue]] damage that may initially trigger the [[nociceptive]] component. When It becomes [[chronic]], the [[pathophysiology]] of pain may gradually shift from [[nociceptive]], a friend signal that should induce self-protection and defense, to [[neuropathic]], with progressive involvement of the [[CNS]].<ref> 10.1007/978-3-319-52539-6_20</ref>
'''Complex:'''Coital pain is greater than the simple peripheral [[tissue]] damage that may initially trigger the [[nociceptive]] component. When It becomes [[chronic]], the [[pathophysiology]] of pain may gradually shift from [[nociceptive]], a friend signal that should induce self-protection and defense, to [[neuropathic]], with progressive involvement of the [[CNS]].<ref> 10.1007/978-3-319-52539-6_20</ref>
* If pain is due to a physical cause, the [[pathophysiology]] of the underlying cause should be considered.
The [[pathophysiology]] of [[dyspareunia]] in males depends on the underlying cause, psychosexual and relational factors.


==References==
==References==

Latest revision as of 16:44, 28 September 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

pathophysiology of genito-pelvic pain/ penetration disorder(GPPPD) can be considered as multifactorial, multisystemic, or complex.

Pathophysiology

Pathophysiology of sexual pain disorders in female can be considered as:[1][2]

  • Multifactorial
  • Multisystemic
  • Complex

Multifactorial:

  • Biological, psychosexual, relational factors can coexist and interact to perpetuate and maintain a woman’s pain response in a woman complaining of coital pain. Over time, these different factors may act as predisposing, precipitating, or perpetuating sexual pain disorders.

Multisystemic: sexual function involves:


Complex:Coital pain is greater than the simple peripheral tissue damage that may initially trigger the nociceptive component. When It becomes chronic, the pathophysiology of pain may gradually shift from nociceptive, a friend signal that should induce self-protection and defense, to neuropathic, with progressive involvement of the CNS.[3]

  • If pain is due to a physical cause, the pathophysiology of the underlying cause should be considered.

The pathophysiology of dyspareunia in males depends on the underlying cause, psychosexual and relational factors.

References

  1. 10.1007/978-3-319-52539-6_20
  2. Graziottin A, Skaper SD, Fusco M (July 2014). "Mast cells in chronic inflammation, pelvic pain and depression in women". Gynecol. Endocrinol. 30 (7): 472–7. doi:10.3109/09513590.2014.911280. PMID 24811097.
  3. 10.1007/978-3-319-52539-6_20