Sjögren's syndrome natural history, complications and prognosis: Difference between revisions
Jump to navigation
Jump to search
Farima Kahe (talk | contribs) |
m (Bot: Removing from Primary care) |
||
| (9 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Sjögren's syndrome}} | {{Sjögren's syndrome}} | ||
{{CMG}} | {{CMG}} {{AE}} {{F.K}} | ||
==Overview== | ==Overview== | ||
The symptoms of Sjögren's syndrome usually develop in the 4th and 5th decade of life, and start with symptoms such as [[ocular]] and [[oral]] dryness. Common complications of Sjögren's syndrome include [[blurred vision]] and [[corneal]] damage, [[optic neuritis]] and [[lymphoma]]. [[Prognosis]] is generally good and presence of low [[complement]] level is associated with a particularly poor [[prognosis]] among patients with Sjögren's syndrome. | |||
==Natural History== | ==Natural History== | ||
===Natural History=== | ===Natural History=== | ||
*The symptoms of | *The symptoms of Sjögren's syndrome usually develop in the 4th and 5th decade of life, and start with symptoms such as [[ocular]] and [[oral]] dryness.<ref name="pmid11920410">{{cite journal |vauthors=Ioannidis JP, Vassiliou VA, Moutsopoulos HM |title=Long-term risk of mortality and lymphoproliferative disease and predictive classification of primary Sjögren's syndrome |journal=Arthritis Rheum. |volume=46 |issue=3 |pages=741–7 |date=March 2002 |pmid=11920410 |doi=10.1002/art.10221 |url=}}</ref> | ||
*If left untreated, 4.3% of patients with Sjögren's syndrome may progress to develop [[non-Hodgkin lymphoma]]. | |||
*If left untreated, | |||
===Complications=== | ===Complications=== | ||
*Common complications of Sjögren's syndrome include: | *Common complications of Sjögren's syndrome include:<ref name="pmid10446879">{{cite journal |vauthors=Voulgarelis M, Dafni UG, Isenberg DA, Moutsopoulos HM |title=Malignant lymphoma in primary Sjögren's syndrome: a multicenter, retrospective, clinical study by the European Concerted Action on Sjögren's Syndrome |journal=Arthritis Rheum. |volume=42 |issue=8 |pages=1765–72 |date=August 1999 |pmid=10446879 |doi=10.1002/1529-0131(199908)42:8<1765::AID-ANR28>3.0.CO;2-V |url=}}</ref><ref name="pmid12169883">{{cite journal |vauthors=Ramos-Casals M, Font J, Garcia-Carrasco M, Brito MP, Rosas J, Calvo-Alen J, Pallares L, Cervera R, Ingelmo M |title=Primary Sjögren syndrome: hematologic patterns of disease expression |journal=Medicine (Baltimore) |volume=81 |issue=4 |pages=281–92 |date=July 2002 |pmid=12169883 |doi= |url=}}</ref><ref name="pmid15028963">{{cite journal |vauthors=Ramos-Casals M, Anaya JM, García-Carrasco M, Rosas J, Bové A, Claver G, Diaz LA, Herrero C, Font J |title=Cutaneous vasculitis in primary Sjögren syndrome: classification and clinical significance of 52 patients |journal=Medicine (Baltimore) |volume=83 |issue=2 |pages=96–106 |date=March 2004 |pmid=15028963 |doi= |url=}}</ref> | ||
**Dental cavities | **[[Dental cavities]] | ||
**Yeast infections | **[[Yeast]] [[infections]] | ||
**Blurred vision and corneal damage | **[[Blurred vision]] and [[corneal]] damage | ||
**Pneumonia | **[[Pneumonia]] | ||
**Bronchitis | **[[Bronchitis]] | ||
**Lymphoma | **[[Lymphoma]] | ||
** | **[[Peripheral neuropathy]] | ||
**Myelitis | **[[Myelitis]] | ||
**Optic neuritis | **[[Optic neuritis]] | ||
===Prognosis=== | ===Prognosis=== | ||
*Prognosis is generally good | *Prognosis is generally good and presence of low [[complement]] level is associated with a particularly poor [[prognosis]] among patients with Sjögren's syndrome.<ref name="pmid15381790">{{cite journal |vauthors=Ramos-Casals M, Brito-Zerón P, Yagüe J, Akasbi M, Bautista R, Ruano M, Claver G, Gil V, Font J |title=Hypocomplementaemia as an immunological marker of morbidity and mortality in patients with primary Sjogren's syndrome |journal=Rheumatology (Oxford) |volume=44 |issue=1 |pages=89–94 |date=January 2005 |pmid=15381790 |doi=10.1093/rheumatology/keh407 |url=}}</ref> | ||
*Primary Sjögren syndrome is associated with lower [[cardiovascular]] risk factors and lower risk of [[cardiovascular]] complications such as myocardial infarction and stroke, in comparison with [[SLE]].<ref name="pmid28080954">{{cite journal |vauthors=Gupta S, Gupta N |title=Sjögren Syndrome and Pregnancy: A Literature Review |journal=Perm J |volume=21 |issue= |pages= |date=2017 |pmid=28080954 |pmc=5267941 |doi=10.7812/TPP/16-047 |url=}}</ref> | |||
*Primary Sjögren syndrome is associated with lower cardiovascular risk factors | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Medicine]] | |||
[[Category:Immunology]] | [[Category:Immunology]] | ||
[[Category:Rheumatology]] | [[Category:Rheumatology]] | ||
[[Category:Up-To-Date]] | |||
Latest revision as of 00:12, 30 July 2020
|
Sjögren's syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Sjögren's syndrome natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Sjögren's syndrome natural history, complications and prognosis |
|
FDA on Sjögren's syndrome natural history, complications and prognosis |
|
CDC on Sjögren's syndrome natural history, complications and prognosis |
|
Sjögren's syndrome natural history, complications and prognosis in the news |
|
Blogs on Sjögren's syndrome natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
The symptoms of Sjögren's syndrome usually develop in the 4th and 5th decade of life, and start with symptoms such as ocular and oral dryness. Common complications of Sjögren's syndrome include blurred vision and corneal damage, optic neuritis and lymphoma. Prognosis is generally good and presence of low complement level is associated with a particularly poor prognosis among patients with Sjögren's syndrome.
Natural History
Natural History
- The symptoms of Sjögren's syndrome usually develop in the 4th and 5th decade of life, and start with symptoms such as ocular and oral dryness.[1]
- If left untreated, 4.3% of patients with Sjögren's syndrome may progress to develop non-Hodgkin lymphoma.
Complications
Prognosis
- Prognosis is generally good and presence of low complement level is associated with a particularly poor prognosis among patients with Sjögren's syndrome.[5]
- Primary Sjögren syndrome is associated with lower cardiovascular risk factors and lower risk of cardiovascular complications such as myocardial infarction and stroke, in comparison with SLE.[6]
References
- ↑ Ioannidis JP, Vassiliou VA, Moutsopoulos HM (March 2002). "Long-term risk of mortality and lymphoproliferative disease and predictive classification of primary Sjögren's syndrome". Arthritis Rheum. 46 (3): 741–7. doi:10.1002/art.10221. PMID 11920410.
- ↑ Voulgarelis M, Dafni UG, Isenberg DA, Moutsopoulos HM (August 1999). "Malignant lymphoma in primary Sjögren's syndrome: a multicenter, retrospective, clinical study by the European Concerted Action on Sjögren's Syndrome". Arthritis Rheum. 42 (8): 1765–72. doi:10.1002/1529-0131(199908)42:8<1765::AID-ANR28>3.0.CO;2-V. PMID 10446879.
- ↑ Ramos-Casals M, Font J, Garcia-Carrasco M, Brito MP, Rosas J, Calvo-Alen J, Pallares L, Cervera R, Ingelmo M (July 2002). "Primary Sjögren syndrome: hematologic patterns of disease expression". Medicine (Baltimore). 81 (4): 281–92. PMID 12169883.
- ↑ Ramos-Casals M, Anaya JM, García-Carrasco M, Rosas J, Bové A, Claver G, Diaz LA, Herrero C, Font J (March 2004). "Cutaneous vasculitis in primary Sjögren syndrome: classification and clinical significance of 52 patients". Medicine (Baltimore). 83 (2): 96–106. PMID 15028963.
- ↑ Ramos-Casals M, Brito-Zerón P, Yagüe J, Akasbi M, Bautista R, Ruano M, Claver G, Gil V, Font J (January 2005). "Hypocomplementaemia as an immunological marker of morbidity and mortality in patients with primary Sjogren's syndrome". Rheumatology (Oxford). 44 (1): 89–94. doi:10.1093/rheumatology/keh407. PMID 15381790.
- ↑ Gupta S, Gupta N (2017). "Sjögren Syndrome and Pregnancy: A Literature Review". Perm J. 21. doi:10.7812/TPP/16-047. PMC 5267941. PMID 28080954.