Diabetes insipidus Diagnostic study of choice: Difference between revisions

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{{Family tree | | | E01 | | | | E02 | | | | | | | | |E01= <br>• Plasma Na+ >143 mEq/L <br>• Posm >295 mOsm/kg H2O <br>• Uosm < Posm | E02= <br>• Plasma Na+ <143 mEq/L <br>• Posm <295 mOsm/kg H2O <br>• Uosm < Posm}}
{{Family tree | | | E01 | | | | E02 | | | | | | | | |E01= <br>• Plasma Na+ >143 mEq/L <br>• Posm >295 mOsm/kg H2O <br>• Uosm < Posm | E02= <br>• Plasma Na+ <143 mEq/L <br>• Posm <295 mOsm/kg H2O <br>• Uosm < Posm}}
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{{Family tree | | | | | | | | | F01 | | | | | | | |F01= '''Water deprivation test''' (minimum for 7 hrs)<br>• Monitor body wt, Posm, Uosm, plasma AVP <br>• Inturrept and measure AVP/Copeptin if; <br>• >3-5% body wt loss <br>• Plasma Na+ > 143 mEq/L <br>• Posm >295 mOsm/kg H2O <br>• Uosm increases to normal }}
{{Family tree | | | |!| | | | | F01 | | | | | | | |F01= '''Water deprivation test''' (minimum for 7 hrs)<br>• Monitor body wt, Posm, Uosm, plasma AVP <br>• Inturrept and measure AVP/Copeptin if; <br>• >3-5% body wt loss <br>• Plasma Na+ > 143 mEq/L <br>• Posm >295 mOsm/kg H2O <br>• Uosm increases to normal }}
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{{Family tree | | | |!| | G01 | | | | G02 | | | | | G01= Uosm < Posm| G02= Uosm > Posm }}
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{{Family tree | | | |!| | |!| | H01 | | | | H02 | | H01= Partial DI| H02= Primary polydipsia }}
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{{Family tree | | | | | | | | I01 | | | | | | | | | I01= '''Desmopressin challange test''' }}

Latest revision as of 21:22, 24 January 2019

Diabetes insipidus Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]

Overview

Diagnostic Study of Choice

Diagnostic approach

Vascular anomalies

 
 
 
 
 
 
 
 
Clinical exam, signs, symptoms
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
24-hrs water balance:
•Confirm polyurea and polydipsia
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
24-hrs urine volume:
• >50-60 ml/kg (age 0-10)
• >40-50 ml/kg (age >10)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Blood and urine test (Na+, Posm, Uosm)
 
 
 
Other diagnostic hypothesis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

• Plasma Na+ >143 mEq/L
• Posm >295 mOsm/kg H2O
• Uosm < Posm
 
 
 

• Plasma Na+ <143 mEq/L
• Posm <295 mOsm/kg H2O
• Uosm < Posm
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Water deprivation test (minimum for 7 hrs)
• Monitor body wt, Posm, Uosm, plasma AVP
• Inturrept and measure AVP/Copeptin if;
• >3-5% body wt loss
• Plasma Na+ > 143 mEq/L
• Posm >295 mOsm/kg H2O
• Uosm increases to normal
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Uosm < Posm
 
 
 
Uosm > Posm
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Partial DI
 
 
 
Primary polydipsia
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Desmopressin challange test