Kaposi's sarcoma staging: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Kaposi's sarcoma}} | {{Kaposi's sarcoma}} | ||
{{CMG}} {{shyam}} {{AE}} {{HL}} | |||
==Overview== | |||
There is no established system for the staging of Kaposi's sarcoma among [[immune]] competent patients. However, the staging of [[AIDS]]-associated Kaposi's sarcoma is based on the AIDS Clinical Trials Group (ACTG) staging system. According to the ACTG staging system, there are 2 groups of AIDS-associated Kaposi's sarcoma based on the [[tumor]] size, patients immune status, and the presence of any systemic illness. | |||
==Staging== | |||
* There is no established system for the staging of Kaposi's sarcoma among [[immune]] competent patients. | |||
* The staging of [[AIDS]]-associated Kaposi's sarcoma is based on the AIDS Clinical Trials Group (ACTG) staging system. According to the ACTG staging system, there are 2 groups of AIDS-associated Kaposi's sarcoma based on the [[tumor]] size, patients immune status, and the presence of any systemic illness.<ref name="Nation">Kaposi Sarcoma Treatment–for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/soft-tissue-sarcoma/hp/kaposi-treatment-pdq#section/_15 Accessed on January, 20 2015</ref><ref name="pmid2671281">{{cite journal| author=Krown SE, Metroka C, Wernz JC| title=Kaposi's sarcoma in the acquired immune deficiency syndrome: a proposal for uniform evaluation, response, and staging criteria. AIDS Clinical Trials Group Oncology Committee. | journal=J Clin Oncol | year= 1989 | volume= 7 | issue= 9 | pages= 1201-7 | pmid=2671281 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2671281 }} </ref><ref name="pmid9294471">{{cite journal| author=Krown SE, Testa MA, Huang J| title=AIDS-related Kaposi's sarcoma: prospective validation of the AIDS Clinical Trials Group staging classification. AIDS Clinical Trials Group Oncology Committee. | journal=J Clin Oncol | year= 1997 | volume= 15 | issue= 9 | pages= 3085-92 | pmid=9294471 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9294471 }} </ref><ref name="cancer"> Sarcoma- Kaposi Guide. Cancer.Net (2015) http://www.cancer.net/cancer-types/sarcoma-kaposi/risk-factors-and-prevention Accessed on January, 20 2015</ref><ref name="america"> How is Kaposi sarcoma staged? American Cancer Association (2015) http://www.cancer.org/cancer/kaposisarcoma/detailedguide/kaposi-sarcoma-staging Accessed on January, 20 2016</ref> | |||
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! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Factors}} | |||
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Good Risk (Subscript 0)}} | |||
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Poor Risk (Subscript 1)}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | | |||
Tumor (T) | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
* Confined to [[skin]] and [[lymph node]]s | |||
* Minimal [[oral]] lesions (non-nodular kaposi's sarcoma confined to the [[palate]]) | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
* Tumor-associated [[edema]] or [[ulceration]] | |||
* Extensive oral lesions present | |||
* [[Gastrointestinal]] lesions present | |||
* Kaposi sarcoma present in other non-nodal [[viscera]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" align=center | | |||
Immune system (I) | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
* CD4 [[T cell]] count ≥ 150/mL | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
* CD4 [[T cell]] count < 150/mL | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" align=center | | |||
Systemic illness (S) | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
* No previous history of opportunistic infection or thrush | |||
* [[B symptoms]] are not present | |||
* Karnofsky performance status score ≥ 70 | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
* Positive history of [[opportunistic infection]]s or [[oral thrush]] | |||
* [[B symptoms]] are present | |||
* Karnofsky performance status score < 70 | |||
|} | |||
* Early stage groups, which are associated with a good risk, include T0I0S0. | |||
* Advanced stage groups, which are associated with a poor risk, include any combination of the TIS system that is not T0I0S0. For example, poor risk groups include T1I0S0, T1I1S0, T1I0S1, T1I1S0, T0I1S0, T1I1S1, etc. Thus, any poor risk feature in the TIS staging system places a patient into the poor risk category overall. | |||
==References== | ==References== | ||
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{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:HIV/AIDS]] | [[Category:HIV/AIDS]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Pulmonology]] | [[Category:Pulmonology]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Vascular medicine]] | |||
[[Category:Surgery]] |
Latest revision as of 03:50, 24 December 2018
Kaposi's sarcoma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Kaposi's sarcoma staging On the Web |
American Roentgen Ray Society Images of Kaposi's sarcoma staging |
Risk calculators and risk factors for Kaposi's sarcoma staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [3]
Overview
There is no established system for the staging of Kaposi's sarcoma among immune competent patients. However, the staging of AIDS-associated Kaposi's sarcoma is based on the AIDS Clinical Trials Group (ACTG) staging system. According to the ACTG staging system, there are 2 groups of AIDS-associated Kaposi's sarcoma based on the tumor size, patients immune status, and the presence of any systemic illness.
Staging
- There is no established system for the staging of Kaposi's sarcoma among immune competent patients.
- The staging of AIDS-associated Kaposi's sarcoma is based on the AIDS Clinical Trials Group (ACTG) staging system. According to the ACTG staging system, there are 2 groups of AIDS-associated Kaposi's sarcoma based on the tumor size, patients immune status, and the presence of any systemic illness.[1][2][3][4][5]
Factors | Good Risk (Subscript 0) | Poor Risk (Subscript 1) |
---|---|---|
Tumor (T) |
|
|
Immune system (I) |
|
|
Systemic illness (S) |
|
|
- Early stage groups, which are associated with a good risk, include T0I0S0.
- Advanced stage groups, which are associated with a poor risk, include any combination of the TIS system that is not T0I0S0. For example, poor risk groups include T1I0S0, T1I1S0, T1I0S1, T1I1S0, T0I1S0, T1I1S1, etc. Thus, any poor risk feature in the TIS staging system places a patient into the poor risk category overall.
References
- ↑ Kaposi Sarcoma Treatment–for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/soft-tissue-sarcoma/hp/kaposi-treatment-pdq#section/_15 Accessed on January, 20 2015
- ↑ Krown SE, Metroka C, Wernz JC (1989). "Kaposi's sarcoma in the acquired immune deficiency syndrome: a proposal for uniform evaluation, response, and staging criteria. AIDS Clinical Trials Group Oncology Committee". J Clin Oncol. 7 (9): 1201–7. PMID 2671281.
- ↑ Krown SE, Testa MA, Huang J (1997). "AIDS-related Kaposi's sarcoma: prospective validation of the AIDS Clinical Trials Group staging classification. AIDS Clinical Trials Group Oncology Committee". J Clin Oncol. 15 (9): 3085–92. PMID 9294471.
- ↑ Sarcoma- Kaposi Guide. Cancer.Net (2015) http://www.cancer.net/cancer-types/sarcoma-kaposi/risk-factors-and-prevention Accessed on January, 20 2015
- ↑ How is Kaposi sarcoma staged? American Cancer Association (2015) http://www.cancer.org/cancer/kaposisarcoma/detailedguide/kaposi-sarcoma-staging Accessed on January, 20 2016