HSPA6: Difference between revisions

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Latest revision as of 20:04, 8 November 2017

Heat shock 70 kDa protein 6 is a protein that in humans is encoded by the HSPA6 gene.^[1]^[2]

References

↑ Leung TK, Hall C, Rajendran M, Spurr NK, Lim L (Mar 1992). "The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1". Genomics. 12 (1): 74–9. doi:10.1016/0888-7543(92)90409-L. PMID 1346391.
↑ "Entrez Gene: HSPA6 heat shock 70kDa protein 6 (HSP70B')".

Leung TK, Rajendran MY, Monfries C, et al. (1990). "The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA". Biochem. J. 267 (1): 125–32. PMC 1131254. PMID 2327978.
Schiller P, Amin J, Ananthan J, et al. (1988). "Cis-acting elements involved in the regulated expression of a human HSP70 gene". J. Mol. Biol. 203 (1): 97–105. doi:10.1016/0022-2836(88)90094-0. PMID 3184191.
Rensing SA, Maier UG (1994). "Phylogenetic analysis of the stress-70 protein family". J. Mol. Evol. 39 (1): 80–6. doi:10.1007/BF00178252. PMID 7545947.
Furlini G, Vignoli M, Re MC, et al. (1994). "Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein". J. Gen. Virol. 75 (1): 193–9. doi:10.1099/0022-1317-75-1-193. PMID 7906708.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Mercier PA, Winegarden NA, Westwood JT (1999). "Human heat shock factor 1 is predominantly a nuclear protein before and after heat stress". J. Cell Sci. 112. ( Pt 16): 2765–74. PMID 10413683.
O'Keeffe B, Fong Y, Chen D, et al. (2000). "Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription". J. Biol. Chem. 275 (1): 279–87. doi:10.1074/jbc.275.1.279. PMID 10617616.
Agostini I, Popov S, Li J, et al. (2000). "Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex". Exp. Cell Res. 259 (2): 398–403. doi:10.1006/excr.2000.4992. PMID 10964507.
Gurer C, Cimarelli A, Luban J (2002). "Specific incorporation of heat shock protein 70 family members into primate lentiviral virions". J. Virol. 76 (9): 4666–70. doi:10.1128/JVI.76.9.4666-4670.2002. PMC 155079. PMID 11932435.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lim MC, Brooke SM, Sapolsky RM (2003). "gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120". Brain Res. Bull. 61 (2): 183–8. doi:10.1016/S0361-9230(03)00113-8. PMID 12832005.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

HSPA6+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[pmid1346391-1] Leung TK, Hall C, Rajendran M, Spurr NK, Lim L (Mar 1992). "The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1". Genomics. 12 (1): 74–9. doi:10.1016/0888-7543(92)90409-L. PMID 1346391.

[entrez-2] "Entrez Gene: HSPA6 heat shock 70kDa protein 6 (HSP70B')".

[1]

[2]

@@ Line 1: / Line 1: @@
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+{{Underlinked|date=March 2017}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''Heat shock 70 kDa protein 6''' is a [[protein]] that in humans is encoded by the ''HSPA6'' [[gene]].<ref name="pmid1346391">{{cite journal |vauthors=Leung TK, Hall C, Rajendran M, Spurr NK, Lim L | title = The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1 | journal = Genomics | volume = 12 | issue = 1 | pages = 74–9 |date=Mar 1992 | pmid = 1346391 | pmc =  | doi =10.1016/0888-7543(92)90409-L  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HSPA6 heat shock 70kDa protein 6 (HSP70B')| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3310| accessdate = }}</ref>
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-{{GNF_Protein_box
- | image = PBB_Protein_HSPA6_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1xqs.
- | PDB = {{PDB2|1xqs}}
- | Name = Heat shock 70kDa protein 6 (HSP70B')
- | HGNCid = 5239
- | Symbol = HSPA6
- | AltSymbols =;
- | OMIM = 140555
- | ECnumber =
- | Homologene =
- | MGIid =
- | GeneAtlas_image1 = PBB_GE_HSPA6_117_at_tn.png
- | GeneAtlas_image2 = PBB_GE_HSPA6_213418_at_tn.png
- | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}}
- | Component =
- | Process = {{GNF_GO|id=GO:0006457 |text = protein folding}} {{GNF_GO|id=GO:0006986 |text = response to unfolded protein}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 3310
-    | Hs_Ensembl = ENSG00000173110
-    | Hs_RefseqProtein = XP_001134322
-    | Hs_RefseqmRNA = XM_001134322
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 1
-    | Hs_GenLoc_start = 159760392
-    | Hs_GenLoc_end = 159763324
-    | Hs_Uniprot = P17066
-    | Mm_EntrezGene =
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA =
-    | Mm_RefseqProtein =
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''Heat shock 70kDa protein 6 (HSP70B')''', also known as '''HSPA6''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HSPA6 heat shock 70kDa protein 6 (HSP70B')| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3310| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 56: / Line 10: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Leung TK, Hall C, Rajendran M, ''et al.'' |title=The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1. |journal=Genomics |volume=12 |issue= 1 |pages= 74-9 |year= 1992 |pmid= 1346391 |doi=  }}
+*{{cite journal   |vauthors=Leung TK, Rajendran MY, Monfries C, etal |title=The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA. |journal=Biochem. J. |volume=267 |issue= 1 |pages= 125–32 |year= 1990 |pmid= 2327978 |doi=  | pmc=1131254  }}
-*{{cite journal  | author=Leung TK, Rajendran MY, Monfries C, ''et al.'' |title=The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA. |journal=Biochem. J. |volume=267 |issue= 1 |pages= 125-32 |year= 1990 |pmid= 2327978 |doi=  }}
+*{{cite journal   |vauthors=Schiller P, Amin J, Ananthan J, etal |title=Cis-acting elements involved in the regulated expression of a human HSP70 gene. |journal=J. Mol. Biol. |volume=203 |issue= 1 |pages= 97–105 |year= 1988 |pmid= 3184191 |doi=10.1016/0022-2836(88)90094-0  }}
-*{{cite journal  | author=Schiller P, Amin J, Ananthan J, ''et al.'' |title=Cis-acting elements involved in the regulated expression of a human HSP70 gene. |journal=J. Mol. Biol. |volume=203 |issue= 1 |pages= 97-105 |year= 1988 |pmid= 3184191 |doi=  }}
+*{{cite journal  |vauthors=Rensing SA, Maier UG |title=Phylogenetic analysis of the stress-70 protein family. |journal=J. Mol. Evol. |volume=39 |issue= 1 |pages= 80–6 |year= 1994 |pmid= 7545947 |doi=10.1007/BF00178252  }}
-*{{cite journal  | author=Rensing SA, Maier UG |title=Phylogenetic analysis of the stress-70 protein family. |journal=J. Mol. Evol. |volume=39 |issue= 1 |pages= 80-6 |year= 1994 |pmid= 7545947 |doi=  }}
+*{{cite journal   |vauthors=Furlini G, Vignoli M, Re MC, etal |title=Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein. |journal=J. Gen. Virol. |volume=75 |issue=  1|pages= 193–9 |year= 1994 |pmid= 7906708 |doi=10.1099/0022-1317-75-1-193  }}
-*{{cite journal  | author=Furlini G, Vignoli M, Re MC, ''et al.'' |title=Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein. |journal=J. Gen. Virol. |volume=75 ( Pt 1) |issue=  |pages= 193-9 |year= 1994 |pmid= 7906708 |doi=  }}
+*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+*{{cite journal  |vauthors=Mercier PA, Winegarden NA, Westwood JT |title=Human heat shock factor 1 is predominantly a nuclear protein before and after heat stress.  | series=112 |journal=J. Cell Sci. |volume=( Pt 16) |issue=  |pages= 2765–74 |year= 1999 |pmid= 10413683 |doi=  }}
-*{{cite journal  | author=Mercier PA, Winegarden NA, Westwood JT |title=Human heat shock factor 1 is predominantly a nuclear protein before and after heat stress. |journal=J. Cell. Sci. |volume=112 ( Pt 16) |issue=  |pages= 2765-74 |year= 1999 |pmid= 10413683 |doi=  }}
+*{{cite journal   |vauthors=O'Keeffe B, Fong Y, Chen D, etal |title=Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription. |journal=J. Biol. Chem. |volume=275 |issue= 1 |pages= 279–87 |year= 2000 |pmid= 10617616 |doi=10.1074/jbc.275.1.279  }}
-*{{cite journal  | author=O'Keeffe B, Fong Y, Chen D, ''et al.'' |title=Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription. |journal=J. Biol. Chem. |volume=275 |issue= 1 |pages= 279-87 |year= 2000 |pmid= 10617616 |doi=  }}
+*{{cite journal   |vauthors=Agostini I, Popov S, Li J, etal |title=Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex. |journal=Exp. Cell Res. |volume=259 |issue= 2 |pages= 398–403 |year= 2000 |pmid= 10964507 |doi= 10.1006/excr.2000.4992 }}
-*{{cite journal  | author=Agostini I, Popov S, Li J, ''et al.'' |title=Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex. |journal=Exp. Cell Res. |volume=259 |issue= 2 |pages= 398-403 |year= 2000 |pmid= 10964507 |doi= 10.1006/excr.2000.4992 }}
+*{{cite journal  |vauthors=Gurer C, Cimarelli A, Luban J |title=Specific incorporation of heat shock protein 70 family members into primate lentiviral virions. |journal=J. Virol. |volume=76 |issue= 9 |pages= 4666–70 |year= 2002 |pmid= 11932435 |doi=10.1128/JVI.76.9.4666-4670.2002  | pmc=155079  }}
-*{{cite journal  | author=Gurer C, Cimarelli A, Luban J |title=Specific incorporation of heat shock protein 70 family members into primate lentiviral virions. |journal=J. Virol. |volume=76 |issue= 9 |pages= 4666-70 |year= 2002 |pmid= 11932435 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  |vauthors=Lim MC, Brooke SM, Sapolsky RM |title=gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120. |journal=Brain Res. Bull. |volume=61 |issue= 2 |pages= 183–8 |year= 2003 |pmid= 12832005 |doi=10.1016/S0361-9230(03)00113-8  }}
-*{{cite journal  | author=Lim MC, Brooke SM, Sapolsky RM |title=gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120. |journal=Brain Res. Bull. |volume=61 |issue= 2 |pages= 183-8 |year= 2003 |pmid= 12832005 |doi=  }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
 }}
 {{refend}}
+{{PDB Gallery|geneid=3310}}
+== External links ==
+* {{MeshName|HSPA6+protein,+human}}
+{{Chaperones}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+[[Category:Heat shock proteins]]
-{{protein-stub}}
+{{gene-1-stub}}
-{{WikiDoc Sources}}

HSPA6: Difference between revisions

Latest revision as of 20:04, 8 November 2017

References

Further reading

External links

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