Vaporizer

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For the device used in surgery, see anaesthetic vaporiser.

For the device commonly called a vaporizer used in humidifying, see humidifier.

A vaporizer (or vapouriser) is a device used to release the active ingredients of plant material, commonly cannabis, or tobacco, or to release therapeutic compounds from herbs (phyto-inhalation; see also: aromatherapy). Vaporizing is an alternative to smoking. Rather than burning the herb, which produces numerous harmful by-products; a vaporizer heats the material, to ideally 180°C (356°F), so that the active compounds contained in the plant melt and phase into an aromatic vapor, not smoke. This vapor ideally contains reduced amounts of particulate matter (tar) and carcinogens such as carbon monoxide. Vapors may be filtered and cooled further using a water pipe or an inline water/ice attachment. Then vapors are inhaled or stored for subsequent inhalations in a "dome" or "balloon". With little to no smoke produced, cooler temperatures, and less material required to achieve the same effect, the irritating/harmful effects of smoking are greatly reduced or eliminated along with second hand smoke by using a vaporizer. This makes vaporizers useful in places where there are public bans on smoking.

The shortcomings of smoked cannabis have been widely viewed as a major obstacle for approval of medical marijuana; in response to the concerns several scientific studies have tried to establish whether vaporizers could offer a clinically reliable and safe method of cannabis use. Though vaporizers show great variations in performance, such studies have always found vaporization superior to smoking, and high-end vaporizers used with High Grade Hybrid Cannabis strains containing elevated levels of THC (the medicinal and psychoactive ingredient in cannabis) have been found to entirely eliminate inhalation of undesired compounds in a manner consistent enough for clinical trials. In comparison to cannabis use methods such as eating, vaporization offers the advantages of inhaling THC: rapid onset, direct delivery into the bloodstream, and the possibility to gradually increase delivery until the desired level is reached, in this manner enabling more effective self-dosage.

Types of vaporizers

Vaporizers are available in many varieties.

Simple vaporizers use a lighter as heat source. Simple vaporizers are inexpensive and have expanded awareness of safer smoking alternatives.

Precise vaporizers use an electric heating element often featuring a temperature control. Some vaporizers even have a dynamic temperature control as seen with systems that use thermocoupled hot air guns. High-end models may cost several hundred dollars.

Broadly, vaporizers can be classified by how they heat the substance:

• by conduction
• by convection

With conduction heating, the substance is placed on a metal plate that is then heated to release the active constituents. The direct contact between hot metal and the herbs can cause them to burn.

With convection heating, the substance itself never touches a heating element. Instead, hot air passes through it heating it rapidly and allowing the release of the active constituents. This method of heating releases far more active constituents than conduction heating, especially if the extraction chamber utilizes Venturi effect design.^{[citation needed]}

Many vaporizers use a tube (called a "whip") that is held to the heat source, and through which the user inhales the vapors. Some vaporizers have a bag or balloon attachment: vapor is blown into the bag, and the user detaches the bag and inhales the contents. Others are more direct extraction and delivery, such as the modular Vaporization "Tools" or "System" approach put forth by VripTech Int. with their VripMaster line which uses a direct venturi or sequential venturi extraction and delivery for maximum potency with delivery via a water pipe or, specialized "Vaporization Water Tool" which is basically a vapor specific water pipe that also holds ice for cooling and condensing the vapor, whilst minimizing oxidation, prior to delivery.

Perhaps the most important classifications for vaporizers include the type of materials used in the heating element, the extraction chambers, and delivery means. Most common "wood box and whip" type vaporizers use a ceramic soldering iron element with a glass extraction chamber and a plastic hose for delivery. This is a low cost and effective approach; however, there are concerns about off-gassing of mercury gas from the solder that is present in wiring of the box and many enthusiasts cringe at the idea of inhaling aromatic vapors through a petroleum based hose for delivery. Some companies, such as VaporBrothers, are now using a higher-grade plastic hose while the makers of the higher end Vapezilla have opted for a silicone hose. The high end Volcano vaporizer uses an aluminum element that works quite well and a metallic extraction chamber with a food grade plastic bag for storage and delivery. Although the FDA considers aluminum heating elements that have not been anodized with a pigment to be compliant, there are concerns about using aluminum in any thermally sensitive application for long durations. The use of metal, a highly conductive material, in the extraction chamber means that to get consistent subsequent vapor extractions one must incrementally dial down the heat to compensate for the heat that is collected in the metal; the upside is that it is very durable. High end thermocoupled heat guns used for vaporization, such as those made by the German company Steinel and sold with the VripTech systems use a medical grade nichrome element encapsulated in ceramic and enclosed in stainless steel.

Health and Medical Use

Regardless of the benefits of medical cannabis, the widely perceived health risks of smoking as a route of administration have been viewed as a major obstacle for the legal approval of cannabis for medical uses, though some studies indicate that the expectorant activity of THC may help the lungs remove much of the inhaled tar through coughing. ^{[citation needed]} In response to the concerns, several studies have aimed to establish whether or not vaporizers could offer a clinically reliable and safe route of administration for cannabis. Though vaporizers show great variations in performance, such studies have consistently found vaporization superior to smoking and with best case (high-end vaporizers used with potent cannabis) results showing an elimination of undesired compounds suitable for clinical trials. ^{[citation needed]} In comparison to other routes of administering cannabis such as eating, vaporization offers the advantages of inhalation - immediate delivery into the bloodstream, rapid onset of effect, and more precise titration, the ability to more accurately control the dosage to produce a desired effect.

Scientific studies

At least five scientific studies have examined vaporizers. Studies have found the release of harmful constituents dramatically reduced ^[1] or completely eliminated ^[2]. Substantial reductions were also found for the M1-volatizer ^[3]. However, a 1996 study ^[4] including two simple vaporizers still found ten times more tar in the vapor than THC, although this was nevertheless up to a 30% improvement compared to the best alternative smoking method.

In 2007, a study by University of California, San Francisco published in the Official Journal of the American Academy of Neurology^[5] examined the effectiveness of a vaporizer that heats cannabis to a temperature between 180 and 200 degrees and found:

In 2006, a study performed by researchers at Leiden University, tested a Volcano Vaporizer with preparations of pure THC and found that:^[2]

When using plant material (crude flower tops), besides THC, several other cannabinoids as well as a range of other plant components including terpenoids were detected in the plant material. However, using pure THC in the Volcano, no degradation products (delta-8-THC (D8-THC), cannabinol (CBN), or unknown compounds) were detected by HPLC analysis. Also, a substantially larger fraction of the THC was delivered to the vapor by using pure THC.

Analysis of the vapor from the Volcano found that using multiple passes it delivered 36% - 61% of the THC in the sample ^[1] - a more recent study using pure cannabinoid preparations achieved a maximum of 54%. ^[2] For comparison, studies of cannabis cigarettes smoked via a smoking machine under varying conditions of puff duration and air speed found very similar efficiencies of 34% to 61%. Consequently, users can achieve the desired effect with a similar amount of material as when smoking.

In a 2001 study testing a device called the M1 Volatizer® ^[3], the researchers found that "it is possible to vaporize medically active THC by heating marijuana to a temperature short of the point of combustion, thereby eliminating or substantially reducing harmful smoke toxins that are normally present in marijuana smoke." The M1 Volatizer, produced THC at a temperature of 365 degrees Fahrenheit (185 degrees Celsius), while completely eliminating three measured combustion products, benzene, toluene and naphthalene. Carbon monoxide and smoke tars were also reduced, but not quantified.

These positive results are in contrast to MAPS/NORML's previous studies into vaporizers which found less encouraging results, leading one to the conclusion that the effectiveness of vaporization varies greatly from vaporizer to vaporizer. See Factors affecting vaporizer output for possible causes of variation.

A 1996 MAPS study ^[4] tested two simple vaporizer models against water pipes and filtered and unfiltered cannabis cigarettes (joints). The smoke produced by each was analyzed for solid particulates (tars) and 3 major cannabinoids. The various smoking methods were then rated based on their cannabinoid-to-tar ratio. The two tested vaporizers performed up to 25% better than unfiltered cannabis cigarettes (second best) in terms of tar delivery. However, both vaporizers produced more than ten times more tars than cannabinoids, which may partly be attributable to the low potency (2.3%) of the NIDA-supplied cannabis used in the study. Surprisingly, the same study found that water pipes (bongs) and filtered cigarettes performed 30% worse than regular, unfiltered joints. The reason was that waterpipes and filters filter out psychoactive THC with the tars, thereby requiring users to smoke more to reach their desired effect. The study did not, however, rule out the possibility that waterpipes could have other benefits, such as filtering out harmful gases such as carbon monoxide.

These studies have not measured the presence of toxic gases, such as ammonia, hydrogen cyanide and carbon monoxide, though previous studies have indicated unquantified decreases in carbon monoxide with vaporization.

Although vaporizers produce cleaner vapors than smoking, they do not completely eliminate respiratory irritation. A puff of strong vaporized cannabis will occasionally cause coughing. This however, could be due to THC itself, which is known to have a strong expectorant effect.

Factors affecting vaporizer extraction and delivery capabilities and the breadth of spectrum of actives deliverable

The wide range of results from tests of different vaporizers suggest that the choice of vaporizer is a major factor in determining extraction and delivery efficiency as well as the amount of harmful byproducts produced, or not produced, as in the case of a superior system. In Cannabis, and many other medicinal plants, the components responsible for the aromatic nature of the plant will often vaporize at a low-end temperature in the range of extraction temperature values for all the bioactive components. In Cannabis, the temperature range across which the actives will vaporize is at least 132 degrees F starting at around 260F where only aromatic compounds of minimal bioactivity will release and going all the way up to 392F with the higher end of this range representing where the cannabinoids of higher bioactivity appear to be released. It is believed that both the total amount of actives delivered as well as the breadth of spectrum delivered per inhalation is critical in determining the value of the delivered dose and, in turn, systems that deliver the highest amount of actives and broadest spectrum of actives per inhalation are believed to be the most effective for medicinal applications: i.e. venturi enhanced extraction / convection based systems.

Proposed factors affecting output include ^[2] , ^[1] :

• temperature;
• specimen density,
• weight, content of water and essential oils,
• consistency of material in the filling chamber
• variety and potency of cannabis used;
• different preparations such as crude flowertops, hashish, hash oil, etc.
• storage time of the vapor
• proportion of THC exhaled (breathing technique)

Not all those have been scientifically tested. Research using the vaporizer found the delivery efficiency highest at around 226 degrees Celsius, falling to about half efficiency at 150 to 180 degrees depending on material ^[2]. The purest preparations produced the highest efficiencies, about 54% for pure THC versus 29% for plant material (female flowertops) with 12% THCA content. Besides THC, several other cannabinoids as well as a range of other plant components including terpenoids were detected in the plant material. Using pure THC in the Volcano, no degradation products (delta-8-THC (D8-THC), cannabinol (CBN), or unknown compounds were detected by HPLC analysis ^[2] .

The longer vapor is stored, the more of the THC is lost as it condenses on the surface of the vaporizer or the balloon. This loss may be negligible over a few minutes but may exceed 50% after 90 minutes ^[2] .

Interestingly, the Leiden Univsersity study ^[2] found that as much as 30%–40% of inhaled THC was not absorbed by the lungs and simply exhaled. However, they did not find large individual differences in the amounts exhaled.

Byproducts

Browns or Duff are the used up herb after vaporization. Instead of being black like ashes they are brown. Though they are in low concentrations, cannaboids may be recovered from an accumulation of Browns using an extraction (such as ethanol) or may be re-vaped.

Scrapings are the buildup of resin in a vaporizer. This buildup may be scraped and vaped for a potent effect, similar to kief.

Vaporizing For Enhanced Lung Capacity Technique

^[6] Although there are a multitude of ways in which to draw vapor from a vaporizer (and much will depend on the type/model of the vaporizer used) the technique used to absorb the maximum amount of THC is also the same way one would enhance lung capacity through exercise. The technique:

• 1.) Expel all air from lungs.
• 2.) Take very deep breath of air, filling from the abdomen up.
• 3.) Expel all air from lungs.
• 4.) Fill lungs to 2/3 their capacity from vaporizer, filling from the abdomen up, drawing from fast to slow
• 5.) Fill rest of lung with air and if applicable remove vaporizer from heat source, continuing to draw off of the vaporizer (in order to cool vaporizer, stopping vaporization when not in use).
• 6.) Hold breath a moment.
• 7.) Inhale one last bit of air.
• 8.) Hold breath a while (as long as comfortable/possible).
• 9.) Exhale slowly and controlled through the nose.

References

1. ↑ ^{1.0 1.1 1.2} Cannabis Vaporizer Combines Efficient Delivery of THC with Effective Suppression of Pyrolytic Compounds By D. Gieringer et.al. Journal of Cannabis Therapeutics, Vol. 4(1) 2004, [1]
2. ↑ ^{2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7} Evaluation of a Vaporizing Device (Volcano) for the Pulmonary Administration of Tetrahydrocannabinol. By A. HAZEKAMP, R. RUHAAK, et.al. JOURNAL OF PHARMACEUTICAL SCIENCES, VOL. 95, NO. 6, JUNE 2006 abstract
3. ↑ ^{3.0 3.1} Cannabis Vaporization: A Promising Strategy for Smoke Harm Reduction. By D. Gieringer, published in Journal of Cannabis Therapeutics Vol. 1#3-4: 153-70 (2001) [Summary].
4. ↑ ^{4.0 4.1} Marijuana Water Pipe and Vaporizer Study. By D. Gieringer. Newsletter of the Multidisciplinary Association for Psychedelic Studies MAPS - Volume 6 Number 3 Summer 1996 [2]
5. ↑ "Marijuana Vaporizer Provides Same Level Of THC, Fewer Toxins, Study Shows", Official Journal of the American Academy of Neurology (summarized by Science Daily), 05-16-2007. Retrieved on 2007-06-06. 
6. ↑ http://www.gotvape.com/vaporizer-blog/2005/07/lung-expansion-through-vaporization.html

See also

• Health issues and the effects of cannabis
• Alcohol without liquid
• Volcano Vaporizer

External links

• Two Medical Studies Find Vaporized Medical Marijuana is Safe and Effective
• NORML/MAPS Study Shows Vaporizer Can Drastically Reduce Toxins in Marijuana Smoke
• Online Guide to Vaporizers
• Vaporizer Information and Directory
• How to build a convection vaporizer
• How to build a conduction vaporizer
• About Eagle Bill, the vaporizer pioneer

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