Tioconazole
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| Tioconazole
| |
| Systematic (IUPAC) name | |
| 1-[2-[(2-chlorothiophen-3-yl) methoxy]- 2-(2,4-dichlorophenyl)- ethyl]imidazole | |
| Identifiers | |
| CAS number | |
| ATC code | D01 G01AF08 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C16H13Cl3N2OS |
| Mol. mass | 387.711 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Topical |
Tioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names. Tioconazole ointments serve to treat women's vaginal yeast infections. They are available in one day doses, as opposed to the 7-day treatments more common in use in the past. Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".
Side effects
Side effects (for the women's formulas) may include temporary burning/irritation of the vaginal area, moderate drowsiness, and headache similar to a sinus headache. Personal Product's 1-Day brand literature also includes upper respiratory infection in its list of side effects. These side effects may be only temporary, and do not interefere with the patient's comfort enough to outweight the end result.
References
Antifungals (D01 and J02) | |
|---|---|
| Antibiotics | Griseofulvin • polyene antimycotics (Natamycin, Nystatin) |
| Topical azoles | imidazoles (Bifonazole, Clomidazole, Clotrimazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole) • triazoles (Fluconazole) • benzimidazole (Thiabendazole) |
| Other topicals | Ciclopirox • Ethylparaben • Flucytosine • Salicylic acid • Selenium sulfide • Tolnaftate • Undecylenic acid • allylamines (Amorolfine, Butenafine, Naftifine, Terbinafine) |
| For systemic use | Griseofulvin • allylamine (Terbinafine) • polyene antimycotic (Amphotericin B) • triazoles (Itraconazole, Posaconazole, Voriconazole) • echinocandins (Anidulafungin, Caspofungin, Micafungin) |
| Other | Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle |
Gynecological anti-infectives and antiseptics (G01) | |
|---|---|
| Antibiotics | polyene antimycotic (Nystatin, Natamycin, Amphotericin B) - Candicidin - Chloramphenicol - Hachimycin - Oxytetracycline - Carfecillin - Mepartricin - Clindamycin - Pentamycin |
| Arsenic compounds | Acetarsol |
| Quinoline derivatives | Diiodohydroxyquinoline - Clioquinol - Chlorquinaldol - Dequalinium - Broxyquinoline - Oxyquinoline |
| Organic acids | Lactic acid - Acetic acid - Ascorbic acid |
| Sulfonamides | Sulfatolamide |
| Imidazole derivatives | Metronidazole - Clotrimazole - Miconazole - Econazole - Ornidazole - Isoconazole - Tioconazole - Ketoconazole - Fenticonazole - Azanidazole - Propenidazole - Butoconazole - Omoconazole - Oxiconazole - Flutrimazole |
| Triazole derivatives | Terconazole |
| Other | Clodantoin - Inosine - Policresulen - Nifuratel - Furazolidone - Methylrosaniline - Povidone-iodine - Ciclopirox - Protiofate - Lactobacillus fermentum - Copper usnate |
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