TAS1R2

Taste receptor, type 1, member 2
Identifiers
Symbol(s)	TAS1R2; TR2; GPR71; T1R2
External IDs	OMIM: 606226 MGI: 1933546 Homologene: 75323
Gene ontology Molecular Function: • receptor activity • metabotropic glutamate, GABA-B-like receptor activity • taste receptor activity • protein heterodimerization activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • response to stimulus • sensory perception of sweet taste
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	80834	83770
Ensembl	ENSG00000179002	na
Uniprot	Q8TE23	na
Refseq	NM_152232 (mRNA) NP_689418 (protein)	XM_980714 (mRNA) XP_985808 (protein)
Location	Chr 1: 19.04 - 19.06 Mb	na
Pubmed search	[1]	[2]

Taste receptor, type 1, member 2, also known as TAS1R2, is a human gene.

See also

• Taste receptor

Further reading

• Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS (2007). "The receptors and cells for mammalian taste.". Nature 444 (7117): 288-94. doi:10.1038/nature05401. PMID 17108952.
• Hoon MA, Adler E, Lindemeier J, et al. (1999). "Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity.". Cell 96 (4): 541-51. PMID 10052456.
• Li X, Staszewski L, Xu H, et al. (2002). "Human receptors for sweet and umami taste.". Proc. Natl. Acad. Sci. U.S.A. 99 (7): 4692-6. doi:10.1073/pnas.072090199. PMID 11917125.
• Spadaccini R, Trabucco F, Saviano G, et al. (2003). "The mechanism of interaction of sweet proteins with the T1R2-T1R3 receptor: evidence from the solution structure of G16A-MNEI.". J. Mol. Biol. 328 (3): 683-92. PMID 12706725.
• Liao J, Schultz PG (2003). "Three sweet receptor genes are clustered in human chromosome 1.". Mamm. Genome 14 (5): 291-301. doi:10.1007/s00335-002-2233-0. PMID 12856281.
• Zhao GQ, Zhang Y, Hoon MA, et al. (2004). "The receptors for mammalian sweet and umami taste.". Cell 115 (3): 255-66. PMID 14636554.
• Galindo-Cuspinera V, Winnig M, Bufe B, et al. (2006). "A TAS1R receptor-based explanation of sweet 'water-taste'.". Nature 441 (7091): 354-7. doi:10.1038/nature04765. PMID 16633339.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.
• Behrens M, Bartelt J, Reichling C, et al. (2006). "Members of RTP and REEP gene families influence functional bitter taste receptor expression.". J. Biol. Chem. 281 (29): 20650-9. doi:10.1074/jbc.M513637200. PMID 16720576.

Template:Membrane-protein-stub This article incorporates text from the United States National Library of Medicine, which is in the public domain.