TAAR1

Trace amine associated receptor 1
Identifiers
Symbol(s)	TAAR1; MGC126874; MGC138399; RP11-295F4.9; TA1; TAR1; TRAR1
External IDs	OMIM: 609333 MGI: 2148258 Homologene: 24938
Gene ontology Molecular Function: • trace-amine receptor activity • receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	134864	111174
Ensembl	ENSG00000146399	ENSMUSG00000056379
Uniprot	Q96RJ0	Q05A85
Refseq	NM_138327 (mRNA) NP_612200 (protein)	NM_053205 (mRNA) NP_444435 (protein)
Location	Chr 6: 133.01 - 133.01 Mb	Chr 10: 23.61 - 23.61 Mb
Pubmed search	[1]	[2]

Trace amine associated receptor 1, also known as TAAR1, is a human gene.

TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001).[supplied by OMIM]

See also

• Trace amine-associated receptor

Further reading

• Borowsky B, Adham N, Jones KA, et al. (2001). "Trace amines: identification of a family of mammalian G protein-coupled receptors.". Proc. Natl. Acad. Sci. U.S.A. 98 (16): 8966-71. doi:10.1073/pnas.151105198. PMID 11459929.
• Bunzow JR, Sonders MS, Arttamangkul S, et al. (2001). "Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor.". Mol. Pharmacol. 60 (6): 1181-8. PMID 11723224.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
• Lindemann L, Ebeling M, Kratochwil NA, et al. (2005). "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.". Genomics 85 (3): 372-85. doi:10.1016/j.ygeno.2004.11.010. PMID 15718104.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.