Spermatid
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| Germinal epithelium of the testicle. 1: basal lamina 2: spermatogonia 3: spermatocyte 1st order 4: spermatocyte 2nd order 5: spermatid 6: mature spermatid 7: Sertoli cell 8: tight junction (blood testis barrier) | |
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| Transverse section of a tubule of the testis of a rat. X 250. | |
| Gray's | subject #258 1243 |
| MeSH | Spermatids |
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Ongoing Trials on Spermatid at Clinical Trials.gov Clinical Trials on Spermatid at Google
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US National Guidelines Clearinghouse on Spermatid
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Overview
The term spermatid refers to the haploid male gametid that results from division of secondary spermatocytes. As a result of meiosis, each spermatid contains only half of the genetic material present in the original primary spermatocyte.
Spermatids are connected together by cytoplasmic material and have superfluous cytoplasmic material around their nuclei.
When formed, early round spermatids must undergo further maturational events in order to develop into spermatozoa, a process termed spermiogenesis (also termed spermeteliosis).
The spermatids begin to grow a tail, develop a thickened mid-piece where the mitochondria become localised and form an acrosome. Spermatid DNA also undergoes packaging, becoming highly condensed. The DNA is packaged firstly with specific nuclear basic proteins, which are subsequently replaced with protamines during spermatid elongation. The resultant tightly packed chromatin is transcriptionally inactive.
Additional images
 Scheme showing analogies in the process of maturation of the ovum and the development of the spermatids (young spermatozoa). |
External links
- Histology at Boston University 17804loa - "Male Reproductive System: testis, early spermatids"
- Histology at Boston University 17805loa - "Male Reproductive System: testis, late spermatids"
- Histology at okstate.edu
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
