Sommelet reaction

Jump to: navigation, search

The Sommelet reaction is an organic reaction in which a benzyl halide is converted to an aldehyde by action of hexamine and water [1][2][3].

The Sommelet reaction

A conceptually related reaction is the Duff reaction (halide replaced by an arene).

In the Kröhnke aldehyde synthesis [4] the oxidizing reagent is is a combination of pyridine and p-nitrosodimethylaniline.


  1. Marcel Sommelet (1913). "Sur un mode de décomposition des halogénoalcoylates d'hexaméthylène - tétramine". Compt. rend. 157: 852–854.
  2. March, Jerry (1985). Advanced Organic Chemistry, Reactions, Mechanisms and Structure, third Edition, John Wiley & Sons. ISBN 0-471-85472-7. 
  3. For an example see: Organic Syntheses, Coll. Vol. 4, p.918 (1963); Vol. 33, p.93 (1953).
  4. F. Kröhnke, Ber., 71B, 2583 (1938).

Navigation WikiDoc | WikiPatient | Up To Date Pages | Recently Edited Pages | Recently Added Pictures

Table of Contents In Alphabetical Order | By Individual Diseases | Signs and Symptoms | Physical Examination | Lab Tests | Drugs

Editor Tools Become an Editor | Editors Help Menu | Create a Page | Edit a Page | Upload a Picture or File | Printable version | Permanent link | Maintain Pages | What Pages Link Here
There is no pharmaceutical or device industry support for this site and we need your viewer supported Donations | Editorial Board | Governance | Licensing | Disclaimers | Avoid Plagiarism | Policies