Skin allergy testing
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Skin allergy testing is a method for medical diagnosis of allergies. A microscopic amount of an allergen is introduced to a patient's skin by various means:
- by pricking the skin with a needle or pin containing a small amount of the allergen ('Prick Testing' or 'Scratch Testing')
- by applying a patch to the skin, where the patch contains the allergen.
If an immuno-response is seen in the form of a rash, hives, urticaria or (worse) anaphylaxis it can be concluded that the patient has a hypersensitivity (or allergy) to that allergen. Further testing can be done to identify the particular allergen.
The "scratch test" as it's called, is still very commonly used as an allergen test. A similar test involving injecting the allergen is also used, but is not quite as common due to increased likelihood of infection and general ineffectiveness by comparison.
See also
Skin end point titration(SET) uses intradermal injection of allergens at increasing concentrations to measure allergic response. To prevent a severe allergic reaction the test is started with a very dilute solution. After 10 minutes the injection site is measured to look for growth of the wheal. 2mm of growth in 10 minutes is considered positive. If 2mm of growth is noted a second injection at a higher concentration is given to confirm the response. The end point is the concentration of antigen that causes an increase in the size of the wheal followed by confirmatory healing. If the wheel grows larger then 13mm no further injection are given since this is considered a major reaction
External links
nl:Allergietest
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
