Systemic inflammatory response syndrome

(Redirected from SIRS)
Jump to navigation Jump to search

For more information about sepsis spectrum syndromes, click here.

WikiDoc Resources for Systemic inflammatory response syndrome

Articles

Most recent articles on Systemic inflammatory response syndrome

Most cited articles on Systemic inflammatory response syndrome

Review articles on Systemic inflammatory response syndrome

Articles on Systemic inflammatory response syndrome in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Systemic inflammatory response syndrome

Images of Systemic inflammatory response syndrome

Photos of Systemic inflammatory response syndrome

Podcasts & MP3s on Systemic inflammatory response syndrome

Videos on Systemic inflammatory response syndrome

Evidence Based Medicine

Cochrane Collaboration on Systemic inflammatory response syndrome

Bandolier on Systemic inflammatory response syndrome

TRIP on Systemic inflammatory response syndrome

Clinical Trials

Ongoing Trials on Systemic inflammatory response syndrome at Clinical Trials.gov

Trial results on Systemic inflammatory response syndrome

Clinical Trials on Systemic inflammatory response syndrome at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Systemic inflammatory response syndrome

NICE Guidance on Systemic inflammatory response syndrome

NHS PRODIGY Guidance

FDA on Systemic inflammatory response syndrome

CDC on Systemic inflammatory response syndrome

Books

Books on Systemic inflammatory response syndrome

News

Systemic inflammatory response syndrome in the news

Be alerted to news on Systemic inflammatory response syndrome

News trends on Systemic inflammatory response syndrome

Commentary

Blogs on Systemic inflammatory response syndrome

Definitions

Definitions of Systemic inflammatory response syndrome

Patient Resources / Community

Patient resources on Systemic inflammatory response syndrome

Discussion groups on Systemic inflammatory response syndrome

Patient Handouts on Systemic inflammatory response syndrome

Directions to Hospitals Treating Systemic inflammatory response syndrome

Risk calculators and risk factors for Systemic inflammatory response syndrome

Healthcare Provider Resources

Symptoms of Systemic inflammatory response syndrome

Causes & Risk Factors for Systemic inflammatory response syndrome

Diagnostic studies for Systemic inflammatory response syndrome

Treatment of Systemic inflammatory response syndrome

Continuing Medical Education (CME)

CME Programs on Systemic inflammatory response syndrome

International

Systemic inflammatory response syndrome en Espanol

Systemic inflammatory response syndrome en Francais

Business

Systemic inflammatory response syndrome in the Marketplace

Patents on Systemic inflammatory response syndrome

Experimental / Informatics

List of terms related to Systemic inflammatory response syndrome

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: SIRS

Overview

In medicine, systemic inflammatory response syndrome (SIRS) is an inflammatory state of the whole body (the "system") without a proven source of infection. It is a serious medical condition.

Definition of SIRS [1], [2]

Criteria for SIRS were agreed in 1992.[3] SIRS can be diagnosed when two or more of the following are present[4]:

  • Heart rate > 90 beats per minute
  • Temperature < 36 (96.8 °F) or > 38 °C (100.4 °F)
  • Tachypnea > 20 breaths per minute or, on blood gas, a PaCO2 < 32 mm Hg
  • White blood cell count < 4000 cells/mm³ or > 12000 cells/mm³ (< 4 x 109 or > 12 x 109 cells/L), or > 10% band forms (immature white blood cells / bandemia).

Difference between SIRS and sepsis

SIRS with a suspected or proven infection is called sepsis.

Simply stated:

SIRS + infection = sepsis

Complications of SIRS

SIRS can result in the multiple organ dysfunction syndrome.

Causes of SIRS

Relation to cytokine storm

SIRS can be considered to be a subset of cytokine storm, a general term (not commonly used in clinical medicine) for cytokine dysregulation.

See also

References

  1. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL (2008). "Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008". Critical Care Medicine. 36 (1): 296–327. doi:10.1097/01.CCM.0000298158.12101.41. PMID 18158437. Retrieved 2012-09-16. Unknown parameter |month= ignored (help)
  2. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992 Jun;101(6):1644-55. PMID 1303622.
  3. "American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis". Crit. Care Med. 20 (6): 864–74. 1992. PMID 1597042.
  4. Tslotou AG, Sakorafas GH, Anagnostopoulos G, Bramis J. Septic shock; current pathogenetic concepts from a clinical perspective. Med Sci Monit. 2005 Mar;11(3):RA76-85. PMID 15735579. Full Text.
  5. Santhanam S, Tolan RW. Sepsis. eMedicine.com, URL: http://www.emedicine.com/ped/topic3033.htm Accessed on Mar 12, 2006.

de:Systemisches inflammatorisches Response-Syndrom Template:WH Template:WS