Resorcinol

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Resorcinol
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Ammu Susheela, M.D. [2]

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Overview

Resorcinol is an anti acne agent that is FDA approved for the treatment of management of acne. Common adverse reactions include hypersensitivity.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

  • Uses for the management of acne
  • Penetrates pores to control acne blemishes, acne pimples, blackheads and whiteheads
  • Helps keep skin clear of new acne blemishes, acne pimples, blackheads and whiteheads.
Directions
  • Shake well
  • Cleanse he skin thoroughly before applying the medication
  • Cover the entire affected area with a thin layer one to three times daily
  • Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor
  • If bothersome dryness or peeling occurs, reduce application to once a day or every other day.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Resorcinol in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Resorcinol in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding FDA-Labeled Use of Resorcinol in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Resorcinol in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Resorcinol in pediatric patients.

Contraindications

There is limited information regarding Resorcinol Contraindications in the drug label.

Warnings

  • For external use only
  • Flammable, Keep away from fire or flame
  • Do not use on broken skin, on large areas of the body

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Resorcinol in the drug label.

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Resorcinol in the drug label.

Drug Interactions

There is limited information regarding Resorcinol Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category

Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Resorcinol in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Resorcinol during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Resorcinol with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Resorcinol with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Resorcinol with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Resorcinol with respect to specific gender populations.

Race

There is no FDA guidance on the use of Resorcinol with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Resorcinol in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Resorcinol in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Resorcinol in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Resorcinol in patients who are immunocompromised.

Administration and Monitoring

Administration

Monitoring

There is limited information regarding Monitoring of Resorcinol in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Resorcinol in the drug label.

Overdosage

There is limited information regarding Chronic Overdose of Resorcinol in the drug label.

Pharmacology

Resorcinol
Resorcinol.png
IUPAC name Benzene-1,3-diol
Other names Resorcin
m-dihydroxybenzene; 1,3-benzenediol; 1,3-Dihydroxybenzene; 3-Hydroxyphenol; m-hydroquinone; m-benzenediol; 3-hydroxycyclohexadien-1-one
Identifiers
CAS number 108-46-3
PubChem 5054
KEGG D00133
ChEBI 27810
ATC code D10AX02,S01AX06
SMILES c1cc(cc(c1)O)O
InChI InChI=1/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
Properties
Molecular formula C6H6O2
Molar mass 110.1 g/mol
Appearance White solid
Density 1.28 g/cm3, solid
Melting point

110 °C, 383 K, 230 °F

Boiling point

277 °C, 550 K, 531 °F

Solubility in water 110 g/100 mL at 20 °C
Acidity (pKa) 9.15[1]
Hazards
EU classification Harmful (Xn)
Dangerous for
the environment (N)
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Mechanism of Action

There is limited information regarding Resorcinol Mechanism of Action in the drug label.

Structure

There is limited information regarding Resorcinol Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Resorcinol in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Resorcinol in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Resorcinol in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Resorcinol in the drug label.

How Supplied

There is limited information regarding Resorcinol How Supplied in the drug label.

Storage

There is limited information regarding Resorcinol Storage in the drug label.

Images

Drug Images

Package and Label Display Panel

This image is provided by the National Library of Medicine.
This image is provided by the National Library of Medicine.

Patient Counseling Information

There is limited information regarding Patient Counseling Information of Resorcinol in the drug label.

Precautions with Alcohol

  • Alcohol-Resorcinol interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

  • ACNOTEX ACNE TREATMENT®[2]

Look-Alike Drug Names

There is limited information regarding Resorcinol Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. Gawron, O., Duggan, M., Grelechi, C., J. Anal. Chem., 1952, 24, 969.
  2. ACNOTEX ACNE TREATMENT - sulfur and resorcinol lotion.

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