Reed-Sternberg cell

(Redirected from Reed-Sternberg cells)
Jump to: navigation, search

WikiDoc Resources for Reed-Sternberg cell

Articles

Most recent articles on Reed-Sternberg cell

Most cited articles on Reed-Sternberg cell

Review articles on Reed-Sternberg cell

Articles on Reed-Sternberg cell in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Reed-Sternberg cell

Images of Reed-Sternberg cell

Photos of Reed-Sternberg cell

Podcasts & MP3s on Reed-Sternberg cell

Videos on Reed-Sternberg cell

Evidence Based Medicine

Cochrane Collaboration on Reed-Sternberg cell

Bandolier on Reed-Sternberg cell

TRIP on Reed-Sternberg cell

Clinical Trials

Ongoing Trials on Reed-Sternberg cell at Clinical Trials.gov

Trial results on Reed-Sternberg cell

Clinical Trials on Reed-Sternberg cell at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Reed-Sternberg cell

NICE Guidance on Reed-Sternberg cell

NHS PRODIGY Guidance

FDA on Reed-Sternberg cell

CDC on Reed-Sternberg cell

Books

Books on Reed-Sternberg cell

News

Reed-Sternberg cell in the news

Be alerted to news on Reed-Sternberg cell

News trends on Reed-Sternberg cell

Commentary

Blogs on Reed-Sternberg cell

Definitions

Definitions of Reed-Sternberg cell

Patient Resources / Community

Patient resources on Reed-Sternberg cell

Discussion groups on Reed-Sternberg cell

Patient Handouts on Reed-Sternberg cell

Directions to Hospitals Treating Reed-Sternberg cell

Risk calculators and risk factors for Reed-Sternberg cell

Healthcare Provider Resources

Symptoms of Reed-Sternberg cell

Causes & Risk Factors for Reed-Sternberg cell

Diagnostic studies for Reed-Sternberg cell

Treatment of Reed-Sternberg cell

Continuing Medical Education (CME)

CME Programs on Reed-Sternberg cell

International

Reed-Sternberg cell en Espanol

Reed-Sternberg cell en Francais

Business

Reed-Sternberg cell in the Marketplace

Patents on Reed-Sternberg cell

Experimental / Informatics

List of terms related to Reed-Sternberg cell

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Reed-Sternberg cells (Lacunar Histiocytes for certain types) are distinctive giant cells found on light microscopy in biopsies from individuals with Hodgkin's lymphoma (aka Hodgkin's disease; a type of lymphoma), and certain other disorders. They are derived from B lymphocytes.

They are named after Dorothy Reed Mendenhall (1874-1964) and Carl Sternberg (1872-1935), who provided the first definitive microscopic descriptions of Hodgkin's disease (Reed, 1902; Sternberg, 1898).

Reed-Sternberg cells are large and are either multinucleated or have a bilobed nucleus (thus resembling an "owl's eye" appearance) with prominent eosinophilic inclusion-like nucleoli. Reed-Sternberg cells are CD30 and CD15 positive, usually negative for CD20 and CD45. The presence of these cells is not pathognomonic for the diagnosis of classical Hodgkin's lymphoma. They can also be found in reactive lymphadenopathy (such as infectious mononucleosis, carbamazepine associated lymphadenopathy) and rarely non-Hodgkin lymphomas.

External links

References

  • Sternberg C. Uber eine eigenartige unter dem Bilde der Pseudoleukamie verlaufende Tuberculose des lymphatischen Apparates. Ztschr Heilk 1898;19:21-90.
  • Reed D. On the pathological changes in Hodgkin's disease, with special reference to its relation to tuberculosis. Johns Hopkins Hosp Rep 1902;10:133-96.

Linked-in.jpg