Ranson criteria
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Ranson criteria is a clinical prediction rule for predicting the severity of acute pancreatitis.
History
It was introduced in 1974.[1]
Usage
Parameters used:
At admission:
- age in years >55years
- white blood cell count > 16000/mcL
- blood glucose > 11 mmol/L (>200 mg/dL)
- serum AST > 250 IU/L
- serum LDH > 350 IU/L
After 48 hours:
- Haematocrit fall > 10%
- increase in BUN by 1.8 or more mmol/L (5 or more mg/dL) after IV fluid hydration
- hypocalcemia (serum calcium < 2.0 mmol/L (<8.0 mg/dL))
- hypoxemia (PO2 < 60 mmHg)
- Base deficit > 4Meq/L
- Estimated fluid sequestration > 6L
The criteria for point assignment is that a certain breakpoint be met at anytime during that 48 hour period, so that in some situations it can be calculated shortly after admission. It is applicable to both biliary and alcoholic pancreatitis.
Interpretation
- If the score >=3, severe pancreatitis likely.
- If the score < 3, severe pancreatitis is unlikely
Or
- Score 0 to 2 : 2% mortality
- Score 3 to 4 : 15% mortality
- Score 5 to 6 : 40% mortality
- Score 7 to 8 : 100% mortality
References
- ↑ Ranson JH, Rifkind KM, Roses DF, Fink SD, Eng K, Spencer FC (1974). "Prognostic signs and the role of operative management in acute pancreatitis". Surgery, gynecology & obstetrics 139 (1): 69-81. PMID 4834279.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
