Orotic acid

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Orotic acid
Orotic-acid-2D-skeletal.png
Identifiers
CAS Number
PubChem CID
DrugBank
E number{{#property:P628}}
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Chemical and physical data
FormulaC5H4N2O4
Molar mass156.098 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Orotic acid, also known as pyrimidinecarboxylic acid or vitamin B13. Historically it was believed to be a vitamin but this is now known not to be the case. It is manufactured in the body by intestinal flora. It is sometimes used as a mineral carrier in some dietary supplements (to increase their bioavailability), most commonly for lithium.

Pathology

A buildup can lead to orotic aciduria.

In ornithine transcarbamoylase deficiency excess carbamoyl phospate is converted into orotic acid. Leading to typical finding of increased urine orotic acid excretion in this disorder of the urea cycle.

See also

External links


de:Orotsäure it:Acido orotico



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