Psammoma body
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A psammoma body is a round collection of calcium, seen microscopically. The term is derived from the Greek word psammos meaning "sand."
Psammoma bodies are commonly seen in certain tumors such as:
- papillary thyroid carcinoma
- papillary renal cell carcinoma
- serous papillary ovarian adenocarcinoma (cystadenocarcinoma)
- endometrial adenocarcinomas(Papillary serous carcinoma ~3%-4%)
- meningioma
- mesothelioma
Psammoma bodies have a laminar appearance.
The origin of psammoma bodies is controversial, but one theory is that the nidus for their formation is a single necrotic tumor cell, upon which layers upon layers of calcium salt deposits are added.
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