Proxibarbital
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| Proxibarbital
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| Systematic (IUPAC) name | |
| 5-(2-hydroxypropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione | |
| Identifiers | |
| CAS number | |
| ATC code | N05 |
| PubChem | |
| Chemical data | |
| Formula | C10H14N2O4 |
| Mol. mass | 226.229 g/mol |
| Synonyms | Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
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Overview
Proxibarbital (Ipronal) is a barbiturate derivative invented in the 1970s. It has sedative, hypnotic and anticonvulsant properties, and was used in the treatment of migraine headaches in a similar manner to butalbital.[1]
References
- ↑ Sulman FG, Pfeifer Y, Tal E. Migraine therapy by enzyme induction with proxibarbital (German). Therapie die Gegenwart. 1976 Dec;115(12):2088-103.
Barbiturates (N01AF, N03AA, N05CA) |
|---|
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AND (Dose)}} Dosing of Proxibarbital • AND (drug interactions)}} Drug interactions with Proxibarbital • AND (side effects)}} Side effects of Proxibarbital • AND (Allergy)}} Allergic reactions to Proxibarbital • AND (overdose)}} Overdose information on Proxibarbital • AND (carcinogenicity)}} Carcinogenicity information on Proxibarbital • AND (pregnancy)}} Proxibarbital in pregnancy • AND (pharmacokinetics)}} Pharmacokinetics of Proxibarbital •
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AND (pharmacogenomics)}} Genetics of Proxibarbital • AND (pharmacogenomics)}} Pharmacogenomics of Proxibarbital • AND (proteomics)}} Proteomics of Proxibarbital
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