Propranolol side effects

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884

Side effects

The following adverse events were observed and have been reported in patients using Propranolol.

Cardiovascular

Central Nervous System

Gastrointestinal

Allergic

Respiratory

Hematologic

Autoimmune

Skin and mucous membranes

Genitourinary

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Cardiovascular:

Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type. Return to top

Central Nervous System:

Lightheadedness; mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics.

For immediate release formulations, fatigue, lethargy, and vivid dreams appear dose related. Return to top

Gastrointestinal:

Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis. Return to top

Allergic:

Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions; pharyngitis and agranulocytosis; erythematous rash; fever combined with aching and sore throat; laryngospasm; respiratory distress. Return to top

Respiratory:

Bronchospasm Return to top

Hematologic:

Agranulocytosis, nonthrombocytopenic purpura, and thrombocytopenic purpura. Return to top

Autoimmune:

Systemic lupus erythematosus (SLE). Return to top

Skin and mucous membranes:

Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasisiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes, and conjunctivae reported for a beta-blocker (practolol) have not been associated with Propranolol. Return to top

Genitourinary:

Male impotence; Peyronie's disease. Return to top

The content of this page is taken from the FDA package insert for this drug and should not be edited.