Prognathism

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Prognathism
Prognathism3.png
ICD-10 K07.1
ICD-9 524.10
DiseasesDB 29354
MeSH D011378

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor in Chief: Berna Zorkun DMD [2]

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [3] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Prognathism is a term used to describe the positional relationship of the mandible and/or maxilla to the skeletal base where either of the jaws protrudes beyond a predetermined imaginary line in the sagittal plane of the skull. In dentistry, oral and maxillofacial surgery and orthodontics this is assessed clinically or radiographically (cephalometrics).

Etymology

The word prognathism derives from Greek pro (forward) and gnathos (jaw).

Presentation

Clinical determinants include soft tissue analysis where the clinician assesses nasolabial angle the relationship of the soft tissue portion of the chin to the nose and the relationship between the upper and lower lips; also used is dental arch relationship assessment such as Angle's classification.

Cephalometric analysis is the most accurate way of determining all types of prognathism as it includes assessments of skeletal base, occlusal plane angulation, facial height, soft tissue assessment and anterior dental angulation. Various calculations and assessments of the information in a cephalometric radiograph allow the clinician to objectively determine dental and skeletal relationships and determine a treatment plan.

Maxillary prognathism is a protrusion of the maxilla, and is also a common feature of many populations. It is not to be confused with micrognathism, although combinations of both may be found. It affects the middle third of the face, causing it to jut out, thereby increasing the facial area. Mandibular prognathism is a protrusion of the mandible, affecting the lower third of the face. Alveolar prognathism is a protrusion of that portion of the maxilla where the teeth are located, in the dental lining of the upper jaw. Prognathism can also be used to describe ways that the maxillary and mandibular dental arches can relate to one another. When there is maxillary and/or alveolar prognathism which causes an alignment of the maxillary incisors significantly anterior to the lower teeth, the condition is called an overbite. When the reverse is the case, and the lower jaw extends forward beyond the upper, the condition is referred to as an underbite.

The vast majority of prognathism in humans is due to normal variation among phenotypes. In human populations where prognathism is not the norm, it may be a malformation, the result of injury, a disease state or a hereditary condition.[1] Prognathism is only a disease if it affects mastication, speech or social function as a byproduct of severely affected aesthetics of the face.

Classification

Alveolar prognathism

Harmful habits, such as thumb sucking or tongue thrusting can result in or exaggerate an alveolar prognathism, causing teeth to misalign. Functional appliances can be used in growing children to help modify bad habits and neuro-muscular function, with the aim of correcting this condition.

Alveolar prognathism can be easily corrected also with fixed orthodontic therapy. However, relapse is quite common, unless the cause is removed or a long term retention is used.

Not all alveolar prognathism is anomalous, and significant differences can be observed among different ethnic groups.[2]

Maxillary Prognathism

In disease states, maxillary prognathism is associated with de Lange Syndrome[3]; however so-called false maxillary prognathism, where there is a lack of growth of the mandible, is by far a more common condition.

Prognathism, if not extremely severe, can be treated in growing patients with orthodontic functional or orthopaedic appliances. In adult patients this condition can be corrected by means of a combined surgical/orthodontic treatment, where most of the time a mandibular advancement is performed. The same can be said for mandibular prognathism.

Mandibular prognathism (progenism)

Pathologic mandibular prognathism is a potentially disfiguring, genetic disorder where the lower jaw outgrows the upper, resulting in an extended chin.

The condition colloquially is known as Habsburg jaw, Habsburg lip or Austrian Lip (see Habsburg) due to its prevalence in that bloodline.[4] The trait is easily traceable in portraits of Habsburg family members.[5] This has provided tools for people interested in studying genetics and pedigree analysis. Most instances are considered polygenetic.[6]

It is alleged to have been derived through a female from the princely Polish family of Piasts, its Masovian branch. The deformation of lips is clearly visible on tomb sculptures of Mazovian Piasts in Warsaw. However this may be, there exists evidence that the trait is longstanding. It is perhaps first observed in Maximilian I (1459-1519).

Traits such as these that were common to royal families are believed to have been passed on and exaggerated over time through royal intermarriage which caused acute inbreeding. Due to the large amount of politically motivated intermarriage among Habsburgs, the dynasty was virtually unparalleled in the degree of its inbreeding. Charles II of Spain is said to have had the most pronounced case of the Habsburg jaw on record. His jaw was so deformed that he was unable to chew.

Many dog breeds have underbite, particularly those with short faces. This may be, as in the case of bulldogs, to a slower growing maxilla in relation to the mandible.

Treatment

The most common treatment for mandibular prognathism is a combination of orthodontics and surgery. The orthodontics can involve braces, removal of teeth, or a bite splint.

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See also

For prognathism as a metric in forensics and ethnic anthropology see

References

  1. http://www.nlm.nih.gov/medlineplus/ency/article/003026.htm
  2. Vioarsdóttir US, O'Higgins P, Stringer C (2002). "A geometric morphometric study of regional differences in the ontogeny of the modern human facial skeleton". J. Anat. 201 (3): 211–29. PMID 12363273.
  3. http://www.medterms.com/script/main/art.asp?articlekey=13301
  4. "OMIM - PROGNATHISM, MANDIBULAR". Retrieved 2007-10-31.
  5. Chudley AE (1998). "Genetic landmarks through philately--the Habsburg jaw". Clin. Genet. 54 (4): 283–4. PMID 9831338.
  6. Wolff G, Wienker TF, Sander H (1993). "On the genetics of mandibular prognathism: analysis of large European noble families". J. Med. Genet. 30 (2): 112–6. PMID 8445614.

Cost Effectiveness of Prognathism

| group5 = Clinical Trials Involving Prognathism | list5 = Ongoing Trials on Prognathism at Clinical Trials.govTrial results on PrognathismClinical Trials on Prognathism at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Prognathism | list6 = US National Guidelines Clearinghouse on PrognathismNICE Guidance on PrognathismNHS PRODIGY GuidanceFDA on PrognathismCDC on Prognathism


| group7 = Textbook Information on Prognathism | list7 = Books and Textbook Information on Prognathism


| group8 = Pharmacology Resources on Prognathism | list8 = AND (Dose)}} Dosing of PrognathismAND (drug interactions)}} Drug interactions with PrognathismAND (side effects)}} Side effects of PrognathismAND (Allergy)}} Allergic reactions to PrognathismAND (overdose)}} Overdose information on PrognathismAND (carcinogenicity)}} Carcinogenicity information on PrognathismAND (pregnancy)}} Prognathism in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Prognathism


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Prognathism | list9 = AND (pharmacogenomics)}} Genetics of PrognathismAND (pharmacogenomics)}} Pharmacogenomics of PrognathismAND (proteomics)}} Proteomics of Prognathism


| group10 = Newstories on Prognathism | list10 = Prognathism in the newsBe alerted to news on PrognathismNews trends on Prognathism


| group11 = Commentary on Prognathism | list11 = Blogs on Prognathism

| group12 = Patient Resources on Prognathism | list12 = Patient resources on PrognathismDiscussion groups on PrognathismPatient Handouts on PrognathismDirections to Hospitals Treating PrognathismRisk calculators and risk factors for Prognathism


| group13 = Healthcare Provider Resources on Prognathism | list13 = Symptoms of PrognathismCauses & Risk Factors for PrognathismDiagnostic studies for PrognathismTreatment of Prognathism

| group14 = Continuing Medical Education (CME) Programs on Prognathism | list14 = CME Programs on Prognathism

| group15 = International Resources on Prognathism | list15 = Prognathism en EspanolPrognathism en Francais

| group16 = Business Resources on Prognathism | list16 = Prognathism in the MarketplacePatents on Prognathism

| group17 = Informatics Resources on Prognathism | list17 = List of terms related to Prognathism


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