Progenitor cell
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
|
WikiDoc Resources for Progenitor cell | |
|
Articles | |
|---|---|
|
Most recent articles on Progenitor cell Most cited articles on Progenitor cell | |
|
Media | |
|
Powerpoint slides on Progenitor cell | |
|
Evidence Based Medicine | |
|
Clinical Trials | |
|
Ongoing Trials on Progenitor cell at Clinical Trials.gov Trial results on Progenitor cell Clinical Trials on Progenitor cell at Google
| |
|
Guidelines / Policies / Govt | |
|
US National Guidelines Clearinghouse on Progenitor cell NICE Guidance on Progenitor cell
| |
|
Books | |
|
News | |
|
Commentary | |
|
Definitions | |
|
Patient Resources / Community | |
|
Patient resources on Progenitor cell Discussion groups on Progenitor cell Patient Handouts on Progenitor cell Directions to Hospitals Treating Progenitor cell Risk calculators and risk factors for Progenitor cell
| |
|
Healthcare Provider Resources | |
|
Causes & Risk Factors for Progenitor cell | |
|
Continuing Medical Education (CME) | |
|
International | |
|
| |
|
Businness | |
|
Experimental / Informatics | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
The term progenitor cell is used in cell biology and developmental biology to refer to immature or undifferentiated cells, typically found in post-natal animals. While progenitor cells share many common features with stem cells, the term is far less restrictive.
Progenitor cells versus Stem cells
Like stem cells, progenitor cells have a capacity for self-renewal and differentiation, although these properties may be limited.
| Feature | Stem cell | Progenitor Cell |
|---|---|---|
| Self-renewal | Unlimited | Can be limited |
| Plasticity | Pluripotent | Unipotent or Multipotent |
Embryonic stem cells are true stem cells in that they are pluripotent and show unlimited capacity for self-renewal. In contrast, many cells termed adult stem cells would be better defined as progenitor cells, as their capacities for unlimited self renewal and plasticity have not been comprehensively demonstrated.
Function of Progenitor cells
The majority of progenitor cells lie dormant or possess little activity in the tissue in which they reside. They exhibit slow growth and their main role is to replace cells lost by normal attrition.
Upon tissue damage or injury, progenitor cells can be activated by growth factors or cytokines, leading to increased cell division important for the repair process.
Examples of Progenitor cells
- Satellite cells found in muscle
- The transit-amplifying neural progenitors of the rostral migratory stream.
- Bone marrow stromal cells, although they are often classed as stem cells due to their high plasticity and potentially unlimited capacity for self renewal.
- Periosteum contains progenitor cells that develop into osteoblasts and chondroblasts.
Stem cells |
|---|
Sources: Embryonic stem cells | Adult stem cells | Cancer stem cells Related articles: Stem cell treatments | Stem cell controversy | Stem cell line | Progenitor cell | Cellular differentiation |
de:Progenitorzellenl:Voorlopercel
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
