Proerythroblast
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| Proerythroblast (Image courtesy of Melih Aktan M.D.) |
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Overview
A proerythroblast (or rubriblast, or pronormoblast) is the earliest of four stages in development of the normoblast.
Laboratory findings
In histology, it is very difficult to distinguish it from the other "blast" cells (lymphoblast, myeloblast, monoblast, and megakaryoblast.) The cytoplasm is blue in an H&E stain, indicating that it is basophilic.
"Pronormoblast" vs. "proerythroblast"
Some sources consider the terms "pronormoblast" and "proerythroblast" to be synonyms.[1] However, other sources[2] consider "proerythroblast" to be a parent term, divided into the following two categories:
- "pronormoblast" - normal develoment
- "promegaloblast" - abnormal development
Additional images
 Blood cell lineage |
Proerythroblasts |
 Proerythroblasts |
References
- ↑ Pronormoblast at eMedicine Dictionary
- ↑ p_35/12668575 at Dorland's Medical Dictionary
External links
- Histology at Boston University 01804loa - "Bone Marrow and Hemopoiesis: bone marrow smear, erythroblast series with proerythroblast"
- Histology at OU 75_11
- Histology at KUMC blood-blood04
- Image and description at purdue.edu
- Histology of "promegaloblast" at marist.edu (pernicious anemia)
- Interactive image at usuarios.lycos.es
- Overview at temple.edu
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
