Premarin
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Synonyms / Brand Names: Estrone Estrone Hydrogen Sulfate, Estrone-sulfate, Estrone Sulphate, Estrone Sulfate Sodium, Estrone Sulfate, Estrone Sodium Sulfate, Estrone Hydrogen Sulfate, Oestrone Sulphate, Sodium Estrone Sulfate, Conestoral, Evex, Hyhorin, Morestin, Par Estro, Premarin, Prempro/Premphase
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
Dosing and Administration
PREMPRO therapy consists of a single tablet to be taken once daily. For treatment of moderate to severe vasomotor symptoms and/or moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered.
- PREMPRO 0.3 mg/1.5 mg
- PREMPRO 0.45 mg/1.5 mg
- PREMPRO 0.625 mg/2.5 mg
- PREMPRO 0.625 mg/5 mg
- PREMPHASE
Patients should be treated with the lowest effective dose. Generally women should be started
at 0.3 mg/1.5 mg PREMPRO daily. Subsequent dosage adjustment may be made based upon
the individual patient response. In patients where bleeding or spotting remains a problem,
after appropriate evaluation, consideration should be given to changing the dose level. This
dose should be periodically reassessed by the healthcare provider
For more information on dosing please refer to Instructions for administration
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.
Media Resources
Slides, Video, Images, MP3, Podcasts, etc.
Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.
International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Premarin
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Publication Resources
Most Recent Articles on Premarin
Review Articles on Premarin
Articles on Premarin in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Premarin
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Trial Resources
Ongoing Trials with Premarin at Clinical Trials.gov
Trial Results with Premarin
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Premarin
Cochrane Collaboration on Premarin
Cost Effectiveness of Premarin
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Media Resources
Powerpoint Slides on Premarin
Images of Premarin
Podcasts & MP3s on Premarin
Videos on Premarin
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Patient Resources
Patient Information from National Library of Medicine
Patient Resources on Premarin
Discussion Groups on Premarin
Patient Handouts on Premarin
Blogs on Premarin
Premarin in the News
Premarin in the Marketplace
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International Resources
Premarin en Español
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The content of this page is taken from the FDA package insert for this drug and should not be edited.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
