Phyllodes tumor
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| Phyllodes tumor Classification and external resources | |
| ICD-10 | C50., D24., D48.6 |
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| ICD-9 | 217 |
| ICD-O: | M9020 |
| DiseasesDB | 3396 |
| eMedicine | med/500 |
| MeSH | D003557 |
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Overview
Phyllodes tumors (from Greek: phullon leaf), also cystosarcoma phyllodes, cystosarcoma phylloides and phylloides tumor, are typically large, fast growing masses that form from the periductal stroma of the breast. They account for less than 1% of all breast neoplasms.
Phyllodes tumors are a fibroepithelial tumor composed of an epithelial and a cellular stromal component. They may be considered benign, borderline, or malignant depending on histologic features including stromal cellularity, infiltration at the tumor's edge, and mitotic activity.
This is predominantly a tumor of adult women, with very few examples reported in adolescents. Occurrence is most common between the ages of 40 and 50, prior to the menopause. This is about 15 years older than the typical age of patients with fibroadenoma, a condition with which Phyllodes tumors may be confused.
The common treatment for phyllodes is wide local excision. Most patients are cured with surgery; the risk of developing local recurrence or metastases is related to the histologic grade, according to the above-named features.
Spectrum
Phyllodes tumors are considered to be on a spectrum of disease[1] that consists of fibroadenoma, fibroadenoma variant and benign phyllodes. Some would extend the spectrum to include malignant phyllodes tumors and frank sarcoma.
References
External links
- Phyllodes Tumor Group - We have over 180 members waiting to give you support and share information.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
