Parafollicular cell

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Parafollicular cell

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Parafollicular cells (also called C cells) are cells in the thyroid which produce and secrete calcitonin.

Embryologically, they associate with the ultimobranchial body, which itself is a ventral derivative of the Fourth Pharyngeal Pouch. The Parafollicular cells themselves are derived from Neural Crest cells.

When parafollicular cells become cancerous, they lead to medullary carcinoma of the thyroid.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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