Norcodeine

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Norcodeine
Clinical data
SynonymsNorcodeine
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC17H19NO3
Molar mass285.337 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Norcodeine is an opiate analogue that is the N-demethylated derivative of codeine.

Norcodeine has relatively little opioid activity in its own right,[1] but is formed as a metabolite of codeine following ingestion.[2]

References

  1. Fraser HF, Isbell H, Van Horn GD. Human pharmacology and addiction liability of norcodeine. Journal of Pharmacology and Experimental Therapeutics. 1960 Jun;129:172-7. PMID 13824628
  2. Posey BL, Kimble SN. High-performance liquid chromatographic study of codeine, norcodeine, and morphine as indicators of codeine ingestion. Journal of Analytical Toxicology. 1984 Mar-Apr;8(2):68-74. PMID 6716978.

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