Nevus
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Ongoing Trials on Nevus at Clinical Trials.gov Clinical Trials on Nevus at Google
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US National Guidelines Clearinghouse on Nevus
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Directions to Hospitals Treating Nevus Risk calculators and risk factors for Nevus
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Naevus
Overview
Nevus is a general term that refers to a number of different (usually benign) pigmented lesions of the skin. Most birthmarks and moles are placed into the category of nevi.
Classification
- Melanocytic nevus: Nevus cells are normally localized in the basal layer of the epidermis. Their proliferation may appear in the form of a:
- Junctional nevus: located just superficial to the junction of the epithelium and the underlying connective tissue. A junctional nevus is flat and is not detected by palpation.
- Compound nevus: located within the interface of the epithelium and the underlying connective tissue. A compound nevus is raised and solid.
- Intradermal nevus: The most common lesion of the skin, these lie exclusively within the dermis. They are regular and round, their cells having a central nucleus and single nucleolus. Some melanocytes may present melanin pigment in the cytoplasm (dark-brown, granular).
- Intramucosal nevus: Although all oral nevi are rare, intramucosal nevi are the most commonly seen there, as they are found most frequently on the hard palate.
- Spider angioma, also known as nevus araneus
- Dysplastic nevus
- Blue nevus
- Blue Rubber Bleb Nevus Syndrome
- Nevus flammeus(port-wine stain)
- Giant Hairy Nevus: These large pigmented (often hairy) congenital nevi are important because of their increased risk (10 to 15%) of conversion into malignant melanoma.
References
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