Methamphetamine precautions
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
List of precautions
Abuse
Hypertension
Fatigue
Limited dosages
Abuse
Methamphetamine has been extensively abused. Tolerance, extreme psychological
dependence, and severe social disability have occurred. There are reports of patients who have
increased the dosage to many times that recommended. Abrupt cessation following prolonged
high dosage administration results in extreme fatigue and mental depression; changes are also
noted on the sleep EEG. Manifestations of chronic intoxication with methamphetamine include
severe dermatoses, marked insomnia, irritability, hyperactivity, and personality changes. The
most severe manifestation of chronic intoxication is psychosis often clinically indistinguishable
from schizophrenia. Return to top
Hypertension
Methamphetamine should be used with caution in patients with even mild hypertension. Return to top
Fatigue
Methamphetamine should not be used to combat fatigue or to replace rest in normal
persons. Return to top
Limited dosages
Prescribing and dispensing of methamphetamine should be limited to the smallest amount
that is feasible at one time in order to minimize the possibility of overdosage. Return to top
The content of this page is taken from the FDA package insert for this drug and should not be edited.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

