Mafosfamide
| Mafosfamide | |
|---|---|
| 200px | |
| IUPAC name | 2-{[2-[bis(2-chloroethyl)amino]-2-oxo- 1-oxa-3-aza-2λ5-phosphacyclohex- 4-yl}sulfanyl]ethanesulfonic acid |
| Identifiers | |
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| MeSH | |
| SMILES | C1COP(=O)(NC1SCCS(=O)(=O)O)N(CCCl)CCCl |
| Properties | |
| Molecular formula | C9H19Cl2N2O5PS2 |
| Molar mass | 401.269 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
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Overview
Mafosfamide (INN) is an oxazaphosphorine (cyclophosphamide-like) alkylating agent under investigation as a chemotherapeutic. Several Phase I trials have been completed.[1][2]
References
- ↑ Intrathecal Mafosfamide. ClinicalTrials.gov. U.S. National Institutes of Health (August 21 2006). Retrieved on 2007-07-13. ClinicalTrials.gov Identifier NCT00062881.
- ↑ Mafosfamide in Treating Patients With Progressive or Refractory Meningeal Tumors. ClinicalTrials.gov. U.S. National Institutes of Health (February 20 2007). Retrieved on 2007-07-13. ClinicalTrials.gov Identifier NCT00031928.
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