MLF1
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(Redirected from MLF1 gene)
| Myeloid leukemia factor 1
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| Identifiers | ||||||||||||||
| Symbol(s) | MLF1; | |||||||||||||
| External IDs | OMIM: 601402 MGI: 1341819 Homologene: 7839 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
| Image:PBB GE MLF1 204783 at tn.png | ||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 4291 | 17349 | ||||||||||||
| Ensembl | ENSG00000178053 | ENSMUSG00000048416 | ||||||||||||
| Uniprot | P58340 | Q3V042 | ||||||||||||
| Refseq | NM_022443 (mRNA) NP_071888 (protein) | NM_001039543 (mRNA) NP_001034632 (protein) | ||||||||||||
| Location | Chr 3: 159.77 - 159.81 Mb | Chr 3: 67.46 - 67.49 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Myeloid leukemia factor 1, also known as MLF1, is a human gene.[1]
References
Further reading
- Yoneda-Kato N, Look AT, Kirstein MN, et al. (1996). "The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1.". Oncogene 12 (2): 265-75. PMID 8570204.
- Lim R, Winteringham LN, Williams JH, et al. (2002). "MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1.". J. Biol. Chem. 277 (43): 40997-1008. doi:10.1074/jbc.M206041200. PMID 12176995.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
- Arber DA, Chang KL, Lyda MH, et al. (2003). "Detection of NPM/MLF1 fusion in t(3;5)-positive acute myeloid leukemia and myelodysplasia.". Hum. Pathol. 34 (8): 809-13. PMID 14506644.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
- Hanissian SH, Akbar U, Teng B, et al. (2004). "cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP.". Oncogene 23 (20): 3700-7. doi:10.1038/sj.onc.1207448. PMID 15116101.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
- Yoneda-Kato N, Tomoda K, Umehara M, et al. (2005). "Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3.". EMBO J. 24 (9): 1739-49. doi:10.1038/sj.emboj.7600656. PMID 15861129.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
- Yoneda-Kato N, Kato JY (2008). "Shuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformation.". Mol. Cell. Biol. 28 (1): 422-34. doi:10.1128/MCB.02335-06. PMID 17967869.
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
