Lytic cycle

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The lytic cycle is one of the two cycles of viral reproduction, the other being the lysogenic cycle. These cycles should not, however, be seen as separate, but rather as somewhat interchangeable. The lytic cycle is typically considered the main method of viral replication, since it results in the destruction of the infected cell.

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Most recent articles on Lytic cycle Most cited articles on Lytic cycle Review articles on Lytic cycle Articles on Lytic cycle in N Eng J Med, Lancet, BMJ
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Powerpoint slides on Lytic cycle Images of Lytic cycle Photos of Lytic cycle Podcasts & MP3s on Lytic cycle Videos on Lytic cycle
Evidence Based Medicine
Cochrane Collaboration on Lytic cycle Bandolier on Lytic cycle TRIP on Lytic cycle
Clinical Trials
Ongoing Trials on Lytic cycle at Clinical Trials.gov Trial results on Lytic cycle Clinical Trials on Lytic cycle at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Lytic cycle NICE Guidance on Lytic cycle NHS PRODIGY Guidance FDA on Lytic cycle CDC on Lytic cycle
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Books on Lytic cycle
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Lytic cycle in the news Be alerted to news on Lytic cycle News trends on Lytic cycle
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Blogs on Lytic cycle
Definitions
Definitions of Lytic cycle
Patient Resources / Community
Patient resources on Lytic cycle Discussion groups on Lytic cycle Patient Handouts on Lytic cycle Directions to Hospitals Treating Lytic cycle Risk calculators and risk factors for Lytic cycle
Healthcare Provider Resources
Symptoms of Lytic cycle Causes & Risk Factors for Lytic cycle Diagnostic studies for Lytic cycle Treatment of Lytic cycle
Continuing Medical Education (CME)
CME Programs on Lytic cycle
International
Lytic cycle en Espanol Lytic cycle en Francais
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Lytic cycle in the Marketplace Patents on Lytic cycle
Experimental / Informatics
List of terms related to Lytic cycle

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Description

The lytic cycle is a three-stage process.

Penetration

To infect a cell, a virus must first enter the cell through the plasma membrane and (if present) the cell wall. Viruses do so by either attaching to a receptor on the cell's surface or by simple mechanical force. The virus then releases its genetic material (either single- or double-stranded DNA or RNA) into the cell.

Biosynthesis

The virus' nucleic acid uses the host cell’s machinery to make large amounts of viral components. In the case of DNA viruses, the DNA transcribes itself into messenger RNA (mRNA) molecules that are then used to direct the cell's ribosomes. One of the first polypeptides to be translated is one that destroys the hosts' DNA. In retroviruses (which inject an RNA strand), a unique enzyme called reverse transcriptase transcribes the viral RNA into DNA, which is then transcribed again into mRNA.

Maturation and lysis

After many copies of viral components are made, they are assembled into complete viruses. The phage then directs production of an enzyme that breaks down the bacteria cell wall and allows fluid to enter. The cell eventually becomes filled with viruses (typically 100-200) and liquid, and bursts, or lyses; thus giving the lytic cycle its name. The new viruses are then free to infect other cells.

Lytic cycle without lysis

Some viruses escape the host cell without bursting the cell membrane, but rather bud off from it by taking a portion of the membrane with them. Because it otherwise is characteristic of the lytic cycle in other steps, it still belongs to this category. Hepatitis C viruses presumably use this method.

v • d • e WikiDoc Research Resources for Lytic cycle
Articles on Lytic cycle	Most recent articles on Lytic cycle • Most cited articles on Lytic cycle • Review articles on Lytic cycle • Articles on Lytic cycle in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Lytic cycle	Powerpoint slides on Lytic cycle • Images of Lytic cycle • Photos of Lytic cycle • Podcasts & MP3s on Lytic cycle • Videos on Lytic cycle
Evidence Based Medicine Regarding Lytic cycle	Cochrane Collaboration on Lytic cycle • Bandolier on Lytic cycle • TRIP on Lytic cycle
Cost Effectiveness of Lytic cycle	Cost Effectiveness of Lytic cycle
Clinical Trials Involving Lytic cycle	Ongoing Trials on Lytic cycle at Clinical Trials.gov • Trial results on Lytic cycle • Clinical Trials on Lytic cycle at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Lytic cycle	US National Guidelines Clearinghouse on Lytic cycle • NICE Guidance on Lytic cycle • NHS PRODIGY Guidance • FDA on Lytic cycle • CDC on Lytic cycle
Textbook Information on Lytic cycle	Books and Textbook Information on Lytic cycle
Pharmacology Resources on Lytic cycle	Dosing of Lytic cycle • Drug interactions with Lytic cycle • Side effects of Lytic cycle • Allergic reactions to Lytic cycle • Overdose information on Lytic cycle • Carcinogenicity information on Lytic cycle • Lytic cycle in pregnancy • Pharmacokinetics of Lytic cycle •
Genetics, Pharmacogenomics, and Proteinomics of Lytic cycle	Genetics of Lytic cycle • Pharmacogenomics of Lytic cycle • Proteomics of Lytic cycle
Newstories on Lytic cycle	Lytic cycle in the news • Be alerted to news on Lytic cycle • News trends on Lytic cycle
Commentary on Lytic cycle	Blogs on Lytic cycle
Patient Resources on Lytic cycle	Patient resources on Lytic cycle • Discussion groups on Lytic cycle • Patient Handouts on Lytic cycle • Directions to Hospitals Treating Lytic cycle • Risk calculators and risk factors for Lytic cycle
Healthcare Provider Resources on Lytic cycle	Symptoms of Lytic cycle • Causes & Risk Factors for Lytic cycle • Diagnostic studies for Lytic cycle • Treatment of Lytic cycle
Continuing Medical Education (CME) Programs on Lytic cycle	CME Programs on Lytic cycle
International Resources on Lytic cycle	Lytic cycle en Espanol • Lytic cycle en Francais
Business Resources on Lytic cycle	Lytic cycle in the Marketplace • Patents on Lytic cycle
Informatics Resources on Lytic cycle	List of terms related to Lytic cycle

de:Lytischer Zyklus

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