He graduated in 1892 as Doctor of Medicine at the Universite Libre de Bruxelles (Brussels, Belgium) and began his work at the Pasteur Institute in Paris in 1894, where, in the laboratory of Elie Metchnikoff, he described phagocytosis of bacteria by white blood cells. In 1898 he described hemolysis evoked by exposure of blood serum to foreign blood cells.
In 1900, he left Paris to found the Pasteur Institute in Brussels, and made his discovery that the bacteriolytic effect of acquired specific antibody is significantly enhanced in vivo by the presence of innate serum components which he termed alexine (but which are now known as complement). This mechanism became the basis for complement-fixation testing methods that enabled the development of serological tests for syphilis (specifically, the development of the Wassermann test by August von Wassermann). The same technique is used today in serologic testing for countless other diseases.
- Jules Bordet
- The Nobel Prize in Physiology or Medicine 1919
- Jules Bordet Institute
- Jules Bordet Museum
Nobel Laureates in Physiology or Medicine
Emil Behring (1901) · Ronald Ross (1902) · Niels Finsen (1903) · Ivan Pavlov (1904) · Robert Koch (1905) · Camillo Golgi / Santiago Ramón y Cajal (1906) · Alphonse Laveran (1907) · Ilya Mechnikov / Paul Ehrlich (1908) · Emil Kocher (1909) · Albrecht Kossel (1910) · Allvar Gullstrand (1911) · Alexis Carrel (1912) · Charles Robert Richet (1913) · Robert Bárány (1914) · Jules Bordet (1919) · August Krogh (1920) · Archibald Hill / Otto Meyerhof (1922) · Frederick Banting / John Macleod (1923) · Willem Einthoven (1924)
|Complete roster · 1901–1925 · 1926–1950 · 1951–1975 · 1976–2000 · 2001–present|
cs:Jules Bordet da:Jules Bordet de:Jules Bordethr:Jules Bordet id:Jules Jean Baptiste Vincent Bordet it:Jules Jean Baptiste Vincent Bordet sw:Jules Bordet nl:Jules Bordetfi:Jules Bordet sv:Jules Bordet
There is no pharmaceutical or device industry support for this site and we need your viewer supported Donations | Editorial Board | Governance | Licensing | Disclaimers | Avoid Plagiarism | Policies