James B. Sumner
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James Batcheller Sumner (November 19, 1887 – August 12, 1955) was an American chemist. He shared the Nobel Prize in Chemistry in 1946 with John Howard Northrop and Wendell Meredith Stanley.
Education
Sumner graduated from Harvard University with a bachelor's degree in 1910 where he was acquainted with prominent chemists Roger Adams, Farrington Daniels, Frank C. Whitmore, James Bryant Conant and Charles Loring Jackson. In 1912, he went to study biochemistry in Harvard Medical School and obtained his Ph.D. degree in 1914. He then worked as Assistant Professor of Biochemistry at the Weill Medical College of Cornell University.
Research
It was at Cornell where Sumner began his research into isolating enzymes in pure form; a feat which had never been achieved before. The enzyme he worked with was urease. Sumner's work was unsuccessful for many years and many of his colleagues were doubtful, believing that what he was trying to achieve was impossible, but in 1926 he discovered that even low molecular weight enzymes could be isolated and crystallized. His successful research brought him to full professorship in 1929.
Awards
In 1937, he was given a Guggenheim Fellowship and he spent five months in Sweden working with Professor Theodor Svedberg. Also that year, John Howard Northrop of the Rockefeller Institute obtained crystalline pepsin making it clear that Sumner had devised a general crystallization method for enzymes and he was awarded the Scheele Medal in Stockholm.
Both Sumner and Northrop shared the Nobel Prize in 1946 for crystallization of enzymes. Sumner was elected to the National Academy of Science in 1948. Sumner died aged 67 of cancer on August 12 1955.
Notes
While hunting at age 17, Sumner was accidentally shot by a companion and as a result his left arm had to be amputated just below the elbow.
External links
Nobel Prize in Chemistry Laureates |
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Theodor Svedberg (1926) • Heinrich Wieland (1927) • Adolf Windaus (1928) • Arthur Harden / Hans von Euler-Chelpin (1929) • Hans Fischer (1930) • Carl Bosch / Friedrich Bergius (1931) • Irving Langmuir (1932) • Harold Urey (1934) • Frédéric Joliot-Curie / Irène Joliot-Curie (1935) • Peter Debye (1936) • Walter Haworth / Paul Karrer (1937) • Richard Kuhn (1938) • Adolf Butenandt / Lavoslav Ružička (1939) • George de Hevesy (1943) • Otto Hahn (1944) • Artturi Virtanen (1945) • James B. Sumner / John Northrop / Wendell Meredith Stanley (1946) • Robert Robinson (1947) • Arne Tiselius (1948) • William Giauque (1949) • Otto Diels / Kurt Alder (1950) |
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