Inferior vena cava syndrome
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| Inferior vena cava syndrome Classification and external resources | |
| Magnetic resonance imaging: There is massive extension of renal cell carcinoma into the inferior vena cava (arrows). Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology | |
| ICD-10 | I87.1 |
| eMedicine | emerg/2718 |
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Inferior vena cava syndrome (IVCS) is a result of obstruction of the inferior vena cava. It can be caused by invasion or compression by a pathological process or by thrombosis in the vein itself.
Frequency
Epidemiological data is elusive owing to the wide variety of clinical presentation. In the U.S., incidence is estimated to be at 5–10 cases per 100'000 per year.
Causes
- Obstruction by deep vein thrombosis or tumors (most commonly renal cell carcinoma)
- Compression through external pressure by neighbouring structures or tumors, either by significantly compressing the vein or by promoting thrombosis by causing turbulence by disturbing the blood flow. This is quite common during the third trimester of pregnancy when the uterus compresses the vein in the right side position.
- Iatrogenic causes may be suspected in patients with a medical history of liver transplantation, vascular catheters, dialysis and other invasive procedures in the vicinity
- Budd-Chiari syndrome
Symptoms
IVCS presents with a wide variety of signs and symptoms, making it difficult to diagnose clinically.
- Edema of the lower extremities
- Tachycardia
- In pregnant women, signs of fetal hypoxia and distress may be seen in the CTG
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

