Hypertension natural history
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Natural History, Complications and Prognosis |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor-In-Chief: Taylor Palmieri
Overview
Hypertension is a well-established risk factor for several serious diseases. Chronic uncontrolled hypertension can be complicated by target organ damage. Most common damaged organs include the cardiovascular system, the brain, the kidneys, and the retina. Even moderate elevation of arterial blood pressure leads to a shortened life expectancy. At severely high mean arterial pressures, 50% or more above average, a person can expect to live no more than just a few years unless appropriately treated.[1]
Complications
Chronic uncontrolled hypertension can be complicated by target organ damage. According to JNC 7, the list of target organ damage includes:[2]
Cardiovascular System
- Left ventricular hypertrophy (LVH)
- Myocardial infarction (MI)
- Heart Failure
- Aneurysm
- Peripheral vascular disease
Brain
Kidneys
- Microalbuminuria
- Proteinuria going to nephrotic-range proteinuria
- Renal failure
Eyes
References
- ↑ Textbook of Medical Physiology, 7th Ed., Guyton & Hall, Elsevier-Saunders, ISBN 0-7216-0240-1, page 220.
- ↑ Cuddy ML (2005). "Treatment of hypertension: guidelines from JNC 7 (the seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure 1).". J Pract Nurs 55 (4): 17-21; quiz 22-3. PMID 16512265.
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