Glycerate 3-phosphate

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Image:Glycerate 3-phosphate.svg

Glycerate 3-phosphate

Systematic (IUPAC) name
(2R)-2-hydroxy-3-phosphonooxy-propanoic acid
Identifiers
CAS number 820-11-1
PubChem         439183
Chemical data
Formula C3H7O7P 
Molar mass 186.058
Complete data

Glycerate 3-phosphate (GP) or 3-phosphoglycerate (3PG) is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle. This chemical is often termed PGA when referring to the Calvin cycle. 3-phosphoglycerate is the resultant of the split of 6 carbon intermediate that is so unstable it splits instantly. And two 3-phosphoglycerate is produced for each molecule of CO2

Glycolysis

1,3-bisphospho-D-glycerate 3-phosphoglycerate kinase 3-phospho-D-glycerate Phosphoglyceromutase 2-phospho-D-glycerate
image:1,3-bisphospho-D-glycerate_wpmp.png   image:3-phospho-D-glycerate_wpmp.png   image:2-phospho-D-glycerate_wpmp.png
ATP ADP
ADP ATP
   
  3-phosphoglycerate kinase   Phosphoglyceromutase


Calvin cycle

In the Calvin cycle, two glycerate 3-phosphate molecules are reduced to form two molecules of glyceraldehyde 3-phosphate (PGAL). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule which is easily reduced.

Amino acid synthesis

Glycerate 3-phosphate is also a precursor for serine, which in turn, can create several other amino acids (such as glycine.)

External links

 v  d  e 
Glycolysis Metabolic Pathway
Glucose Hexokinase Glucose-6-phosphate Phosphoglucoisomerase Fructose 6-phosphate Phosphofructokinase Fructose 1,6-bisphosphate Fructose bisphosphate aldolase Dihydroxyacetone phosphate Glyceraldehyde 3-phosphate Triosephosphate isomerase Glyceraldehyde 3-phosphate Glyceraldehyde phosphate dehydrogenase
ATP ADP ATP ADP NAD+ + Pi NADH + H+
+ 2
NAD+ + Pi NADH + H+
1,3-Bisphosphoglycerate Phosphoglycerate kinase 3-Phosphoglycerate Phosphoglycerate mutase 2-Phosphoglycerate Enolase Phosphoenolpyruvate Pyruvate kinase Pyruvate Pyruvate dehydrogenase Acetyl-CoA
ADP ATP H2O ADP ATP CoA + NAD+ NADH + H+ + CO2
2 2 2 2 2 2
ADP ATP H2O
Template:Metabolic pathway stub

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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