Gadodiamide
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| Image:Gadodiamide.png | |
| Image:Gadodiamide2.png | |
| Gadodiamide
| |
| Systematic (IUPAC) name | |
| 2-[bis[2-(carboxylatomethyl-(methylcarbamoylmethyl)amino)ethyl]amino]acetate; gadolinium(+3) cation | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C16H28GdN5O9 |
| Mol. mass | 591.672g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | negligible |
| Metabolism | not metabolized |
| Half life | 77.8 minutes |
| Excretion | renal |
| Therapeutic considerations | |
| Pregnancy cat. |
C(US) |
| Legal status | |
| Routes | i.v. |
Gadodiamide is a gadolinium based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. It is commonly marketed under the trade name Omniscan.
Uses
Gadodiamide is used to visualize blood vessels during MRI procedures. The use of gadodiamide in these scans allows for the diagnosis of intracranial lesions or blood-brain barrier anomalies.[1] It is a high osmolarity contrast agent at 789 mOsmol per kg of water.
Gadolinium based agents may cause a toxic reaction known as NSF in patients with severe kidney problems.
References
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
