GPR3

G protein-coupled receptor 3
Identifiers
Symbol(s)	GPR3; ACCA
External IDs	OMIM: 600241 MGI: 101908 Homologene: 31303
Gene ontology Molecular Function: • rhodopsin-like receptor activity • receptor activity Cellular Component: • integral to plasma membrane • membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • G-protein signaling, adenylate cyclase activating pathway
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	2827	14748
Ensembl	ENSG00000181773	ENSMUSG00000049649
Uniprot	P46089	Q3USD4
Refseq	NM_005281 (mRNA) NP_005272 (protein)	NM_008154 (mRNA) NP_032180 (protein)
Location	Chr 1: 27.59 - 27.59 Mb	Chr 4: 132.48 - 132.48 Mb
Pubmed search	[1]	[2]

G protein-coupled receptor 3, also known as GPR3, is a human gene.

Further reading

• Eggerickx D, Denef JF, Labbe O, et al. (1995). "Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.". Biochem. J. 309 ( Pt 3): 837-43. PMID 7639700.
• Iismaa TP, Kiefer J, Liu ML, et al. (1995). "Isolation and chromosomal localization of a novel human G-protein-coupled receptor (GPR3) expressed predominantly in the central nervous system.". Genomics 24 (2): 391-4. doi:10.1006/geno.1994.1635. PMID 7698767.
• Heiber M, Docherty JM, Shah G, et al. (1995). "Isolation of three novel human genes encoding G protein-coupled receptors.". DNA Cell Biol. 14 (1): 25-35. PMID 7832990.
• Marchese A, Docherty JM, Nguyen T, et al. (1995). "Cloning of human genes encoding novel G protein-coupled receptors.". Genomics 23 (3): 609-18. doi:10.1006/geno.1994.1549. PMID 7851889.
• Song ZH, Modi W, Bonner TI (1996). "Molecular cloning and chromosomal localization of human genes encoding three closely related G protein-coupled receptors.". Genomics 28 (2): 347-9. doi:10.1006/geno.1995.1154. PMID 8530049.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Uhlenbrock K, Huber J, Ardati A, et al. (2003). "Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells.". Cell. Physiol. Biochem. 13 (2): 75-84. doi:10.1159/000070251. PMID 12649592.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.