GPR125

G protein-coupled receptor 125
Identifiers
Symbol(s)	GPR125; PGR21; TEM5L
External IDs	MGI: 1917943 Homologene: 19235
Gene ontology Molecular Function: • receptor activity • G-protein coupled receptor activity • protein binding Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • neuropeptide signaling pathway
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	166647	70693
Ensembl	ENSG00000152990	ENSMUSG00000029090
Uniprot	Q8IWK6	Q3V2C4
Refseq	XM_001131071 (mRNA) XP_001131071 (protein)	XM_132089 (mRNA) XP_132089 (protein)
Location	Chr 4: 22 - 22.13 Mb	Chr 5: 50.25 - 50.35 Mb
Pubmed search	[1]	[2]

G protein-coupled receptor 125, also known as GPR125, is a human gene.

Further reading

• Seandel M, et al. (2007). "Generation of functional multipotent adult stem cells from GPR125+ germline progenitors.". Nature 449 (7160): 346-50. PMID 17882221.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Fredriksson R, Gloriam DE, Höglund PJ, et al. (2003). "There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.". Biochem. Biophys. Res. Commun. 301 (3): 725-34. PMID 12565841.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
• Yamamoto Y, Irie K, Asada M, et al. (2004). "Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.". Oncogene 23 (22): 3889-97. doi:10.1038/sj.onc.1207495. PMID 15021905.
• Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.". Genomics 84 (1): 23-33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.