GPR119

G protein-coupled receptor 119
Identifiers
Symbol(s)	GPR119; GPCR2; MGC119957; hGPCR2
External IDs	OMIM: 300513 MGI: 2668412 Homologene: 18670
Gene ontology Molecular Function: • lysosphingolipid and lysophosphatidic acid receptor activity • receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • insulin secretion
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	139760	236781
Ensembl	ENSG00000147262	ENSMUSG00000051209
Uniprot	Q8TDV5	Q2ABS2
Refseq	NM_178471 (mRNA) NP_848566 (protein)	NM_181751 (mRNA) NP_861416 (protein)
Location	Chr X: 129.35 - 129.35 Mb	Chr X: 44.92 - 44.92 Mb
Pubmed search	[1]	[2]

G protein-coupled receptor 119, also known as GPR119, is a human gene.

GPR119 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003).[supplied by OMIM]

Further reading

• Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence.". FEBS Lett. 520 (1-3): 97-101. PMID 12044878.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Fredriksson R, Höglund PJ, Gloriam DE, et al. (2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives.". FEBS Lett. 554 (3): 381-8. PMID 14623098.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325-37. doi:10.1038/nature03440. PMID 15772651.
• Overton HA, Babbs AJ, Doel SM, et al. (2006). "Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents.". Cell Metab. 3 (3): 167-75. doi:10.1016/j.cmet.2006.02.004. PMID 16517404.