Familial adenomatous polyposis other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]

Overview

Colonoscopy is considered as a gold standard for evaluating intestine, diagnostic and therapeutic approaches. Tissue biopsy and polypectomy could be done during colonoscopy. Findings on a colonoscopy and flexible sigmoidoscopy suggestive of familial adenomatous polyposis include visual detection of multiple colon polyps. Colonoscopy has 0.02% mortality and 0.2% morbidity 0.2%. Colonoscopy has side effects including pain, risk of perforation and bleeding.

Other Diagnostic Studies

Colon polyp on a short stalk. Attribute to Stephen Holland, M.D., Naperville Gastroenterology, Naperville, IL, USA. By Original uploader was Rsabbatini at en.wikipediaLater version(s) were uploaded by Kd4ttc at en.wikipedia. - Transfered from en.wikipedia, CC BY 2.5[6]


Familial adenomatous polyposis as seen on Sigmoidoscopy. Released into public domain on permission of patient. By Samir at the English language Wikipedia, CC BY-SA 3.0[8]


  • Capsule endoscopy may be helpful in the diagnosis of familial adenomatous polyposis.[9]
    • Findings on a capsule endoscopy suggestive of colon polyps include visual detection of multiple polyps.
    • It assesses the location, size, and number of small-bowel polyps.
    • It is recommended for the surveillance of jejunal-ileal polyps in selected patients.
    • Relative contraindication for capsule endoscopy is abdominal surgery.
  • Forward-viewing and side-viewing endoscopy may be helpful in the diagnosis of familial adenomatous polyposis.
    • Forward-viewing and side-viewing endoscopy are used for surveillance of periampullary and duodenal polyposis.

References

  1. 1.0 1.1 Arnesen, R. B.; Ginnerup-Pedersen, B.; Poulsen, P. B.; von Benzon, E.; Adamsen, S.; Laurberg, S.; Hart-Hansen, O. (2016). "Cost-effectiveness of computed tomographic colonography: a prospective comparison with colonoscopy". Acta Radiologica. 48 (3): 259–266. doi:10.1080/02841850601182139. ISSN 0284-1851.
  2. Ponugoti, Prasanna; Lin, Jingmei; Odze, Robert; Snover, Dale; Kahi, Charles; Rex, Douglas K. (2017). "Prevalence of sessile serrated adenoma/polyp in hyperplastic-appearing diminutive rectosigmoid polyps". Gastrointestinal Endoscopy. 85 (3): 622–627. doi:10.1016/j.gie.2016.10.022. ISSN 0016-5107.
  3. Johnson, David H.; Kisiel, John B.; Burger, Kelli N.; Mahoney, Douglas W.; Devens, Mary E.; Ahlquist, David A.; Sweetser, Seth (2017). "Multitarget stool DNA test: clinical performance and impact on yield and quality of colonoscopy for colorectal cancer screening". Gastrointestinal Endoscopy. 85 (3): 657–665.e1. doi:10.1016/j.gie.2016.11.012. ISSN 0016-5107.
  4. O'Brien, Michael J. (2007). "Hyperplastic and Serrated Polyps of the Colorectum". Gastroenterology Clinics of North America. 36 (4): 947–968. doi:10.1016/j.gtc.2007.08.007. ISSN 0889-8553.
  5. Moreno, Courtney C.; Mittal, Pardeep K.; Henson, Nicholas L.; Baumgarten, Deborah A.; Alexander, Lauren F.; Hanes, Timothy S.; Small, William C.; Kitajima, Hiroumi D.; Kang, Jian; Votaw, John R.; Oshinski, John N.; Dixon, W. Thomas (2014). "Optimal section thickness for detection of polyps at MR: resolution phantom study". Abdominal Imaging. 40 (6): 1451–1456. doi:10.1007/s00261-014-0331-6. ISSN 0942-8925.
  6. "File:Polyp.jpeg - Wikimedia Commons". External link in |title= (help)
  7. Shussman, N.; Wexner, S. D. (2014). "Colorectal polyps and polyposis syndromes". Gastroenterology Report. 2 (1): 1–15. doi:10.1093/gastro/got041. ISSN 2052-0034.
  8. "File:Familial adenomatous polyposis as seen on sigmoidoscopy.jpg - Wikimedia Commons".
  9. Iaquinto, Gaetano; Fornasarig, Mara; Quaia, Michele; Giardullo, Nicola; D'Onofrio, Vittorio; Iaquinto, Salvatore; Di Bella, Simone; Cannizzaro, Renato (2008). "Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis". Gastrointestinal Endoscopy. 67 (1): 61–67. doi:10.1016/j.gie.2007.07.048. ISSN 0016-5107.

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