Erythromycin side effects

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753

List of Side effects

QT syndrome

Hepatic Dysfunction

Congenital Syphilis

Rhabdomyolysis

Pseudomembranous Colitis

Overgrowth of Clostridia

---

QT syndrome

There have been reports of prolonged QT syndrome in geriatric patients receiving oral erythromycin products. Return to top

Hepatic Dysfunction

There have been reports of hepatic dysfunction, with or without jaundice, occurring in patients receiving oral erythromycin products. Return to top

Congenital Syphilis

There have been reports suggesting that erythromycin does not reach the fetus in adequate concentration to prevent congenital syphilis. Infants born to women treated during pregnancy with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen. Return to top

Rhabdomyolysis

Rhabdomyolysis with or without renal impairment has been reported in seriously ill patients receiving erythromycin concomitantly with lovastatin. Therefore, patients receiving concomitant lovastatin and erythromycin should be carefully monitored for creatine kinase (CK) and serum transaminase levels. Return to top

Pseudomembranous Colitis

Pseudomembranous colitis has been reported with nearly all antibacterial agents, including erythromycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Return to top

Overgrowth of Clostridia

Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia. Studies indicate that a toxin produced by Clostridium difficile is one primary cause of “antibiotic-associated colitis”. Return to top

---

The content of this page is taken from the FDA package insert for this drug and should not be edited.