Enteropathy-associated T-cell lymphoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

Enteropathy-associated T-cell Lymphoma (EATL), also enteropathy-type T-cell lymphoma (ETTL), is a type of T-cell non-hodgkin lymphoma that affects the small intestine, it is composed of large lymphoid cells. Enteropathy-associated T-cell lymphoma has two subtypes, type I enteropathy-associated T-cell lymphoma which has a strong association with celiac disease and it is more common in western countries and type II enteropathy-associated T-cell lymphoma which is mostly found among the Asian population. Genes involved in the pathogenesis of this disease include 8q24, T-cell receptor (TCR) beta and gamma, and 16q genes. CT scan findings of EATL patients include bowel wall thickening, mesenteric fat intiltration.


CT scan

  • CT scan may be helpful in the diagnosis of enteropathy-associated T-cell lymphoma.[1]
  • Findings on CT scan suggestive of enteropathy-associated T-cell lymphoma include:[2][3]

Refrences

  1. Enteropathy-associated T-cell lymphoma. Surveillance, Epidemiology, and End Results Program. http://seer.cancer.gov/seertools/hemelymph/51f6cf56e3e27c3994bd5315/. Accessed on January 26, 2016
  2. Lee, Hyun Ju; Im, Jung-Gi; Goo, Jin Mo; Kim, Kyoung Won; Choi, Byung Ihn; Chang, Kee Hyun; Han, Joon Koo; Han, Moon Hee (2003). "Peripheral T-Cell Lymphoma: Spectrum of Imaging Findings with Clinical and Pathologic Features1". RadioGraphics. 23 (1): 7–26. doi:10.1148/rg.231025018. ISSN 0271-5333.. Accessed on January 28, 2016
  3. Di Sabatino, A.; Biagi, F.; Gobbi, P. G.; Corazza, G. R. (2012). "How I treat enteropathy-associated T-cell lymphoma". Blood. 119 (11): 2458–2468. doi:10.1182/blood-2011-10-385559. ISSN 0006-4971.. Accessed on January 28, 2016